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  1. <Medical Topics
    Infectious Disease
    Biology of Infectious Disease
    • Introduction to the Biology of Infectious Diseases
      • Reference
    • Host Defense Mechanisms Against Infection
      • Natural Barriers Against Infection
        • Skin
        • Mucous membranes
        • Respiratory tract
        • Gastrointestinal tract
        • Genitourinary tract
        • Natural barriers reference
      • Nonspecific Immune Responses (Innate Immune Responses)
      • Specific Immune Responses (Adaptive Immune Responses)
      • Host Genetic Factors
    • Factors Facilitating Microbial Invasion
      • Virulence Factors
        • Capsule
        • Enzymes
        • Toxins
        • Other factors
      • Microbial Adherence
        • Biofilm
      • Antimicrobial Resistance
        • Reference
      • Defects in Host Defense Mechanisms
        • Mechanisms
    • Manifestations of Infection
      • Clinical manifestations
      • Hematologic manifestations
      • Other organ systems
      • Reference
    • Fever
      • Pathophysiology
        • Consequences of fever
      • Etiology
        • Infectious causes
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
        • Treatment reference
      • Geriatrics Essentials
        • Reference
      • Key Points
    • Fever of Unknown Origin (FUO)
      • General reference
      • Etiology
        • Etiology reference
      • Evaluation
        • History
        • History reference
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Testing reference
      • Treatment
      • Geriatrics Essentials
      • Key Points
    • Abscesses
      • Etiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Bacteremia
      • Etiology
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Key Points
    Laboratory Diagnosis of Infectious Disease
    • Introduction to Laboratory Diagnosis of Infectious Disease
      • Reference
    • Microscopy
      • Gram Stain
      • Acid-Fast and Modified Acid-Fast Stains
      • Fluorescent Stains
      • Wet Mounts
      • India Ink Stain
      • Warthin-Starry Stain and Dieterle Stain
      • Wright Stain and Giemsa Stain
      • Trichrome Stain (Gomori-Wheatley Stain) and Iron Hematoxylin Stain
    • Culture
      • Specimen Collection
        • References
      • Special Considerations for Culture
        • Anaerobes
        • Mycobacteria
        • Viruses
        • Fungi
    • Susceptibility Testing
      • Qualitative methods
      • Semiquantitative methods
      • Nucleic acid–based methods
    • Immunologic Tests for Infectious Disease
      • Agglutination tests
      • Complement fixation
      • Enzyme immunoassays
      • Precipitation tests
      • Western blot test
    • Non-Nucleic Acid–Based Identification Methods for Infectious Disease
      • Serologic assays
      • Chromatographic methods
      • Mass spectrometry
    • Nucleic Acid–Based Identification Methods for Infectious Disease
      • Unamplified testing
      • Nucleic acid amplification
    Immunization
    • Mpox Vaccine
      • General references
      • Preparations
      • Indications
      • Contraindications and Precautions
        • Contraindications and precautions reference
      • Administration
      • Adverse Effects
        • Adverse effects reference
      • More Information
    • Diphtheria-Tetanus-Pertussis Vaccine
      • Preparations
      • Indications
        • Indications references
      • Contraindications and Precautions
        • Contraindications and precautions reference
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Tetanus-Diphtheria Vaccine
      • Preparations
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Meningococcal Vaccine
      • General reference
      • Preparations
      • Indications
        • Indications reference
      • Contraindications and Precautions
      • Dose and Administration
        • MenACWY vaccine
        • MenB vaccine
        • Dose and administration references
      • Adverse Effects
      • More Information
    • Haemophilus influenzae Type b (Hib) Vaccine
      • Preparations
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Hepatitis A (HepA) Vaccine
      • Reference
      • Preparations
      • Indications
        • Indications reference
      • Contraindications and Precautions
      • Dose and Administration
        • Dose and administration references
      • Adverse Effects
      • More Information
    • Hepatitis B (HepB) Vaccine
      • General references
      • Preparations
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
        • Dose and administration references
      • Adverse Effects
      • More Information
    • Human Papillomavirus (HPV) Vaccine
      • General reference
      • Preparations
        • Preparations reference
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
        • Dose and administration references
      • Adverse Effects
      • More Information
    • Influenza Vaccine
      • Preparations
        • Preparations reference
      • Indications
      • Contraindications and Precautions
        • Contraindications and precautions reference
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Measles, Mumps, and Rubella (MMR) Vaccine
      • General references
      • Preparations
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
      • Adverse Effects
        • Adverse effects references
      • More Information
    • Pneumococcal Vaccine
      • Preparations
        • Preparations reference
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Administration
        • Administration reference
      • Adverse Effects
      • More Information
    • Poliomyelitis Vaccine
      • Preparations
        • Preparations reference
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
      • Adverse Effects
        • Adverse effects reference
      • More Information
    • Varicella Vaccine
      • General references
      • Preparations
      • Indications
        • Indications references
      • Contraindications and Precautions
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Herpes Zoster Vaccine
      • Preparations
      • Indications
        • Indications reference
      • Contraindications and Precautions
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Rotavirus Vaccine
      • Preparations
      • Indications
      • Contraindications and Precautions
      • Dose and Administration
        • Dose and administration references
      • Adverse Effects
      • More Information
    • COVID-19 Vaccine
      • Preparations
      • Indications
      • Contraindications and Precautions
        • Contraindications and precautions reference
      • Dose and Administration
        • Dose and administration references
      • Adverse Effects
        • Adverse effects references
      • More Information
    • Ebola Vaccine
      • General references
      • Preparations
        • Preparations reference
      • Indications
        • Indications references
      • Contraindications and Precautions
        • Contraindications and precautions references
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Chikungunya Vaccine
      • Preparations
      • Indications
        • Indications reference
      • Contraindications and Precautions
        • Contraindications and precautions references
      • Dose and Administration
      • Adverse Effects
      • More Information
    • Respiratory Syncytial Virus (RSV) Vaccine
      • General references
      • Preparations
      • Indications
        • Indications reference
      • Contraindications and Precautions
      • Dose and Administration
        • Dose and administration references
      • Adverse Effects
      • More Information
    • Overview of Immunization
      • Vaccines
      • References
      • Vaccine Administration
        • Simultaneous administration of different vaccines
        • Vaccine administration references
      • Restrictions, Precautions, and High-Risk Groups
        • Allergy
        • Guillain-Barré syndrome
        • Fever or other acute illness
        • Pregnancy
        • Immunocompromise
        • Asplenia
        • Transplantation
        • Blood product use
        • Restrictions, precautions, and high-risk groups references
      • Vaccine Safety and Hesitancy
      • Immunization for Travelers
      • More Information
    • Passive Immunization
      • Human immune globulin (IG)
      • References
      • Hyperimmune globulin
    Anaerobic Bacteria
    • Overview of Anaerobic Bacteria
      • Testing
    • Overview of Clostridial Infections
      • Pathophysiology
      • Diseases Caused by Clostridia
    • Actinomycosis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prognosis
      • Key Points
    • Botulism
      • Sources of toxin
      • General references
      • Symptoms and Signs
        • Foodborne botulism
        • Wound botulism
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Antitoxin
        • Treatment references
      • Prevention
      • Key Points
    • Clostridioides difficile Infection
      • General references
      • Pathophysiology
        • Pathophysiology reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment of recurrences
        • Prevention
        • Treatment references
      • Key Points
    • Clostridial Intra-Abdominal and Pelvic Infections
      • Symptoms and Signs
        • Sepsis
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Clostridial Necrotizing Enteritis
      • Neutropenic enterocolitis (typhlitis)
      • Neonatal necrotizing enterocolitis
    • Clostridium perfringens Food Poisoning
      • Diagnosis
      • Treatment
    • Clostridial Soft-Tissue Infections
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Key Points
    • Tetanus
      • General references
      • Pathophysiology
      • Symptoms and Signs
        • Spasms
        • Autonomic instability
        • Causes of death
        • Localized tetanus
        • Tetanus neonatorum (neonatal tetanus)
      • Diagnosis
      • Treatment
        • General principles
        • Wound care
        • Antitoxin and toxoid
        • Management of muscle spasms
        • Management of autonomic dysfunction
        • Antibiotics
        • Supportive care
        • Treatment references
      • Prognosis
        • Prognosis reference
      • Prevention
        • Prevention reference
      • Key Points
    • Mixed Anaerobic Infections
      • Etiology
      • Pathophysiology
        • Diagnosis reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Oropharyngeal anaerobic infections and lung abscesses
        • Gastrointestinal (GI) or female pelvic anaerobic infections
      • Prevention
      • Key Points
    • Infant Botulism
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
    Approach to Parasitic Infections
    • Approach to Parasitic Infections
      • Protozoa
      • Microsporidia
      • Helminths
      • Ectoparasites
      • General references
      • Diagnosis
        • Gastrointestinal tract parasites
        • Serologic testing for parasitic infections
        • Diagnosis references
      • Treatment
      • Prevention
      • More Information
    Arboviruses, Arenaviridae, and Filoviridae
    • Overview of Arbovirus, Arenavirus, and Filovirus Infections
      • General references
      • Treatment
      • Prevention
        • Vector control and bite prevention
        • Vaccination
        • Prevention references
      • More Information
    • Dengue
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Prevention
        • Prevention references
      • Key Points
    • Hantavirus Infection
      • General references
      • Hemorrhagic Fever With Renal Syndrome
        • Symptoms and Signs
        • Diagnosis
        • Treatment
        • Prognosis
      • Hantavirus Pulmonary Syndrome
        • Symptoms and Signs
        • Diagnosis
        • Treatment
        • Prognosis
    • Lassa Fever
      • General reference
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
      • Treatment
      • Prognosis
        • Prognosis reference
      • Prevention
        • Prevention reference
      • Key Points
    • Lymphocytic Choriomeningitis
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Key Points
    • Marburg and Ebola Virus Infections
      • Transmission of Marburg and Ebola viruses
      • General references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Prevention
        • Prevention references
      • Key Points
    • Yellow Fever
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Prevention
        • Prevention references
      • Key Points
    • Other Arbovirus Infections
      • Mayaro Disease
        • Mayaro disease references
      • Oropouche Fever
        • Oropouche fever references
      • Tick-Borne Encephalitis
        • Tick-borne encephalitis references
      • Powassan Virus
        • Powassan virus references
      • Other tick-borne viruses
        • Other tick-borne viruses references
      • California Encephalitis Serogroup Viruses
        • California encephalitis serogroup viruses references
      • Omsk Hemorrhagic Fever and Kyasanur Forest Disease
        • Omsk hemorrhagic fever and Kyasanur Forest disease references
      • Rift Valley Fever
        • Rift Valley fever references
    • Zika Virus (ZV) Infections
      • Epidemiology
        • Epidemiology reference
      • Transmission of Zika Virus
        • Transmission references
      • Symptoms and Signs
        • Congenital Zika virus infection
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Prevention
        • Prevention of transmission via mosquitoes
        • Prevention of sexual transmission
        • Prevention references
      • Key Points
    • West Nile Virus
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
      • More Information
    • Chikungunya Disease
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Prevention
        • Prevention reference
    • Dengue Hemorrhagic Fever/Dengue Shock Syndrome
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Key Points
    Bacteria and Antibacterial Medications
    • Aminoglycosides
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Overview of Beta-Lactams
      • Beta-Lactamases
        • Ambler classification class A
        • Ambler classification class B
        • Ambler classification class C
        • Ambler classification class D
      • Beta-Lactamase Inhibitors
    • Chloramphenicol
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
    • Daptomycin
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
        • Adverse effects reference
      • Dosing Considerations
    • Fluoroquinolones
      • Pharmacokinetics
      • Indications
      • Contraindications
        • Contraindications reference
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Lincosamides, Oxazolidinones, and Streptogramins
    • Macrolides
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Metronidazole and Tinidazole
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
      • More Information
    • Mupirocin
    • Nitrofurantoin
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
    • Polypeptide Antibiotics: Bacitracin, Colistin, Polymyxin B
      • Resistance
      • Indications
        • Indications references
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
        • Dosing considerations references
    • Rifamycins
      • Rifabutin, Rifampin, and Rifapentine
        • Pharmacokinetics
        • Indications
        • Contraindications
        • Use During Pregnancy and Breastfeeding
        • Adverse Effects
        • Dosing Considerations
      • Rifaximin
      • More Information
    • Sulfonamides
      • Resistance
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Tetracyclines
      • Pharmacokinetics
      • Indications
      • Contraindications
        • Contraindications references
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Tigecycline
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Vancomycin
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
        • Dosing considerations reference
      • More Information
    • Spectinomycin
    • Carbapenems
      • Carbapenem resistance
      • Use During Pregnancy and Breastfeeding
    • Cephalosporins
      • Pharmacokinetics
      • Indications
        • First-generation cephalosporins
        • Second-generation cephalosporins and cephamycins
        • Third-generation cephalosporins
        • Fourth-generation cephalosporins
        • Anti-MRSA cephalosporins
        • Other cephalosporins
        • Indications references
      • Contraindications
        • Contraindications references
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
        • Adverse effects reference
    • Monobactams
    • Penicillins
      • Resistance
      • Pharmacokinetics
        • Pharmacokinetics reference
      • Indications
        • Penicillin G–like antibiotics
        • Amoxicillin and ampicillin
        • Penicillinase-resistant (antistaphylococcal) penicillins
        • Broad-spectrum (antipseudomonal) penicillin
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
        • Hypersensitivity
        • Rashes
        • Other adverse effects
      • Dosing Considerations
    • Fosfomycin
      • Pharmacokinetics
      • Indications
        • Indications references
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Clindamycin
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
        • Adverse effects references
      • Dosing Considerations
    • Linezolid and Tedizolid
      • Linezolid
        • Contraindications
        • Use During Pregnancy and Breastfeeding
        • Adverse Effects
      • Tedizolid
        • Use During Pregnancy and Breastfeeding
        • More Information
    • Quinupristin and Dalfopristin
      • Safety Warning
    • Trimethoprim and Sulfamethoxazole
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Lipoglycopeptides
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use During Pregnancy and Breastfeeding
      • Adverse Effects
      • Dosing Considerations
    • Lefamulin
      • Pharmacokinetics
      • Indications
      • Contraindications
      • Use in Pregnancy and Breastfeeding
      • Adverse Effects
    • Overview of Bacteria
      • Morphology
      • Staining
      • Encapsulation
      • Oxygen requirements
    • Overview of Antibacterial Medications
      • Selection and Use of Antibiotics
        • Spectrum of activity
        • Effectiveness
        • Route
        • Special populations
        • Duration
        • Complications
        • Selection and use of antibiotics references
      • Antibiotic Resistance
    Cestodes (Tapeworms)
    • Overview of Tapeworm Infections
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
    • Dipylidium caninum Infection
      • Treatment reference
    • Echinococcosis
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Key Points
    • Hymenolepis nana (Dwarf Tapeworm) Infection
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
    • Hymenolepis diminuta Infection
      • Reference
    • Coenurosis (Taenia multiceps, Taenia serialis, or Taenia brauni Infection)
      • Reference
    • Sparganosis
      • General references
    • Taenia saginata (Beef Tapeworm) Infection
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
    • Taenia Solium (Pork Tapeworm) Infection and Cysticercosis
      • Symptoms and Signs
        • Intestinal infection
        • Cysticercosis
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment of intestinal infection
        • Treatment of neurocysticercosis
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
    • Diphyllobothriasis (Fish Tapeworm Infection)
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
        • Prevention reference
    • Taenia asiatica (Asian Tapeworm) Infection
      • Reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
    Chlamydiae and Mycoplasmas
    • Chlamydiae
      • General reference
      • Chlamydia trachomatis
        • C. trachomatis references
      • Chlamydia pneumoniae
        • Chlamydia pneumoniae reference
      • Chlamydia psittaci
        • Chlamydia psittaci reference
      • Key Points
    • Mycoplasmas
      • Mycoplasma pneumoniae
      • Mycoplasma genitalium
      • Mycoplasma hominis
    COVID-19
    • COVID-19
      • Transmission
      • Symptoms and Signs
        • Risk factors for severe disease
        • Complications
        • Symptom resolution
        • Symptoms and signs references
      • Diagnosis
        • Evaluating symptomatic patients
        • Diagnosis references
      • Treatment
        • Early treatment for patients with mild to moderate COVID-19 who are high risk for progression to severe illness
        • Treatment for patients with severe COVID-19
        • Treatment references
      • Post–COVID-19 Infection
        • Post–COVID-19 infection reference
      • Prevention
        • COVID-19 vaccination
        • Monoclonal antibody
        • Exposure prevention
        • Prevention references
      • More Information
    Enteroviruses
    • Overview of Enterovirus Infections
      • Parechoviruses
      • Diseases Caused by Enteroviruses
      • Aseptic meningitis
      • Acute flaccid myelitis (AFM)
      • Hemorrhagic conjunctivitis
      • Myopericarditis
      • Respiratory infections
      • Rash
      • Neonatal infection
      • References
      • Diagnosis
      • Treatment
        • Treatment references
    • Epidemic Pleurodynia
      • Symptoms
      • Diagnosis
      • Treatment
    • Hand-Foot-and-Mouth Disease (HFMD)
      • References
    • Herpangina
      • Symptoms
      • Diagnosis
      • Treatment
    • Poliomyelitis
      • References
      • Pathophysiology
      • Symptoms and Signs
        • Minor poliovirus infection
        • Poliovirus aseptic meningitis without paralysis
        • Paralytic poliomyelitis
      • Diagnosis
      • Treatment
      • Prognosis
        • Prognosis references
      • Prevention
        • Prevention reference
      • Key Points
      • More Information
    • Postpoliomyelitis Syndrome
      • Reference
    Extraintestinal Protozoa
    • African Trypanosomiasis
      • General references
      • Pathophysiology
      • Symptoms and Signs
        • Cutaneous
        • Hemolymphatic
        • Central nervous system
      • Diagnosis
      • Treatment
        • Treatment of T. b. gambiense HAT
        • Treatment of T. b. rhodesiense HAT
        • Treatment references
      • Prevention
      • Key Points
      • More Information
    • Babesiosis
      • General reference
      • Pathogenesis
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Prevention
        • Tick bite prevention
      • Key Points
      • More Information
    • Chagas Disease
      • General references
      • Pathophysiology
      • Symptoms and Signs
        • Acute stage
        • Chronic indeterminate stage
        • Chronic stage with cardiac or gastrointestinal involvement
        • Symptoms and signs references
      • Diagnosis
        • Ancillary testing in patients with chronic Chagas disease
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
      • More Information
    • Leishmaniasis
      • General references
      • Pathophysiology
        • Cutaneous leishmaniasis
        • Mucosal leishmaniasis
        • Visceral leishmaniasis
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Cutaneous leishmaniasis
        • Mucosal leishmaniasis
        • Visceral leishmaniasis
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
      • More Information
    • Malaria
      • General references
      • Pathophysiology
        • Falciparum malaria
        • Resistance to infection
        • Pathophysiology reference
      • Symptoms and Signs
        • P. falciparum manifestations
        • P. vivax, P. ovale, P. malariae, and P. knowlesi manifestations
        • Manifestations in patients taking chemoprophylaxis
        • Symptoms and signs reference
      • Diagnosis
        • Severity of malaria
        • Diagnosis references
      • Treatment
        • P. falciparum malaria
        • P. vivax malaria or P. ovale malaria
        • Severe malaria
        • Treatment references
      • Prevention of Relapses of P. vivax or P. ovale Malaria
      • Prevention
        • Prophylactic measures against mosquitoes
        • Chemoprophylaxis with antimalarial drugs
        • Vaccination
        • Prevention reference
      • Key Points
    • Toxoplasmosis
      • General references
      • Pathophysiology
        • Pathophysiology reference
      • Symptoms and Signs
        • Acute toxoplasmosis
        • CNS toxoplasmosis
        • Congenital toxoplasmosis
        • Ocular toxoplasmosis
        • Disseminated infection and non-CNS involvement
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment of immunocompetent patients
        • Treatment of immunocompromised patients
        • Treatment of ocular toxoplasmosis
        • Treatment of pregnant patients
        • Treatment of infants with congenital toxoplasmosis
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
    • Introduction to Extraintestinal Protozoa
    • Overview of Free-Living Amebas
    • Amebic Keratitis
      • General references
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
      • More Information
    • Granulomatous Amebic Encephalitis
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis of Acanthamoeba infections
        • Diagnosis of B. mandrillaris infections
        • Diagnosis of S. pedata infections
        • Diagnosis reference
      • Treatment
      • Key Points
    • Primary Amebic Meningoencephalitis
      • General reference
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Key Points
    Fungal Infections
    • Overview of Fungal Infections
      • Primary fungal infections
      • Opportunistic fungal infections
      • Diagnosis
    • Antifungal Medications
      • Amphotericin B
        • Formulations
        • Adverse effects
        • Amphotericin B reference
      • Azole Antifungals
        • Fluconazole
        • Itraconazole
        • Voriconazole
        • Posaconazole
        • Isavuconazonium sulfate (isavuconazole)
        • Oteseconazole
        • Azole antifungals reference
      • Echinocandins
      • Flucytosine
    • Aspergillosis
      • General references
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Key Points
    • Blastomycosis
      • General reference
      • Symptoms and Signs
        • Pulmonary blastomycosis
        • Extrapulmonary disseminated blastomycosis
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Key Points
    • Candidiasis
      • Disseminated candidiasis
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Invasive candidiasis
        • Esophageal candidiasis
        • Treatment reference
      • Key Points
    • Coccidioidomycosis
      • General reference
      • Pathophysiology
        • Risk factors for progressive coccidioidomycosis
      • Symptoms and Signs
        • Primary coccidioidomycosis
        • Progressive coccidioidomycosis
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Key Points
    • Cryptococcosis
      • General references
      • Pathophysiology
      • Symptoms and Signs
        • Central nervous system
        • Lungs
        • Skin
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Patients without advanced HIV infection
        • Patients with advanced HIV infection
        • Treatment references
      • Key Points
    • Histoplasmosis
      • General reference
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Acute primary histoplasmosis
        • Chronic cavitary histoplasmosis
        • Severe disseminated histoplasmosis
        • Treatment references
      • Prognosis
      • Key Points
    • Mucormycosis
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
    • Mycetoma
      • General references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • More Information
    • Paracoccidioidomycosis
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
    • Chromoblastomycosis
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
    • Sporotrichosis
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
    • Miscellaneous Opportunistic Fungi
      • Trichosporon species
      • Malassezia species
      • Talaromyces marneffei
      • Fusarium species and Scedosporium apiospermum
    • Phaeohyphomycosis
      • General reference
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
    Gram-Negative Bacilli
    • Introduction to Gram-Negative Bacilli
    • Overview of Bartonella Infections
    • Brucellosis
      • Complications
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
      • More Information
    • Campylobacter Infections
      • Complications
      • References
      • Symptoms and Signs
      • Diagnosis
      • Treatment
    • Cholera
      • References
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
      • Treatment
        • Fluid replacement
        • Antimicrobials
        • Treatment references
      • Prevention
        • Cholera vaccines
        • Prevention references
      • Key Points
      • More Information
    • Escherichia coli Infections
      • Diseases caused by E. coli
      • Diagnosis
      • Treatment
        • Drug resistance
        • Treatment reference
    • Haemophilus Infections
      • Diseases caused by Haemophilus species
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
      • More Information
    • HACEK Infections
      • Reference
    • Klebsiella, Enterobacter, and Serratia Infections
      • Treatment
        • Treatment reference
      • More Information
    • Legionella Infections
      • Transmission of Legionella species
      • Transmission reference
      • Diseases caused by Legionella species
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Key Points
      • More Information
    • Melioidosis
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
      • Treatment
      • Key Points
    • Pertussis
      • Complications caused by pertussis
      • Parapertussis
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Prevention
        • Immunization
        • Postexposure prophylaxis
      • Key Points
      • More Information
    • Plague and Other Yersinia Infections
      • Transmission
      • Symptoms and Signs
        • Bubonic plague
        • Pneumonic plague
        • Septicemic plague
        • Pestis minor
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
      • More Information
      • Other Yersinia Infections
        • Reference
    • Proteeae Infections
    • Pseudomonas and Related Infections
      • Epidemiology
      • Diseases Caused by Pseudomonas
        • Skin and soft-tissue infections
        • Respiratory tract infections
        • Other infections
        • Bacteremia
      • Diagnosis
      • Treatment
        • Localized infection
        • Systemic infection
        • Treatment references
      • Key Points
    • Overview of Salmonella Infections
    • Shigellosis
      • References
      • Symptoms and Signs
        • Complications of shigellosis
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Prevention
        • Prevention reference
      • Key Points
    • Cat-Scratch Disease
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
    • Oroya Fever and Verruga Peruana
      • Oroya Fever
        • Reference
      • Verruga Peruana
    • Bacillary Angiomatosis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
    • Trench Fever
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
    • Noncholera Vibrio Infections
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Key Points
    • Infection by Escherichia coli O157:H7 and Other Enterohemorrhagic E. coli (EHEC)
      • Epidemiology
        • Epidemiology reference
      • Pathophysiology
        • Pathophysiology reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Prevention
      • Key Points
    • Typhoid Fever
      • Transmission
      • SalmonellaSalmonella carrier state
      • General references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Carriers
        • Treatment reference
      • Prognosis
        • Prognosis reference
      • Prevention
        • Vaccination
        • Prevention reference
      • Key Points
    • Nontyphoidal Salmonella Infections
      • Risk factors
      • Diseases caused by nontyphoidal Salmonella species
      • Reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Carriers
        • Treatment reference
      • Prevention
      • Key Points
    • Tularemia
      • Symptoms and Signs
        • Pneumonic tularemia
      • Diagnosis
      • Treatment
      • Prognosis
        • Prognosis reference
      • Prevention
        • Prevention reference
      • Key Points
    Gram-Negative Cocci and Coccobacilli
    • Acinetobacter Infections
      • General references
      • Diseases Caused by Acinetobacter
        • Risk factors
        • Drug resistance in Acinetobacter
        • Diseases caused by Acinetobacter reference
      • Treatment
        • Treatment references
      • Key Points
    • Kingella Infections
      • Diseases Caused by Kingella
        • Diseases caused by Kingella reference
      • Diagnosis
      • Treatment
        • Treatment reference
    • Meningococcal Diseases
      • References
      • Diseases Caused by Meningococci
        • Reference
      • Pathophysiology
        • Risk factors
        • Pathophysiology references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
        • Antibiotic prophylaxis
        • Vaccination
        • Prevention references
      • Key Points
      • More Information
    • Moraxella catarrhalis Infection
      • References
    • Oligella Infections
    Gram-Positive Cocci
    • Pneumococcal Infections
      • Serotypes
      • Risk factors for pneumococcal infection
      • General references
      • Diseases Caused by Pneumococci
        • Pneumococcal acute otitis media
        • Pneumococcal pneumonia
        • Pneumococcal paranasal sinusitis
        • Pneumococcal bacteremia
        • Pneumococcal meningitis
        • Pneumococcal endocarditis
        • Pneumococcal septic arthritis
        • Spontaneous pneumococcal peritonitis
        • Diseases caused by pneumococci references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Meningeal pneumococcal infections
        • Nonmeningeal pneumococcal infections
        • Treatment reference
      • Prevention
        • Pneumococcal vaccines
        • Prophylactic antibiotics
        • Prevention references
      • Key Points
    • Staphylococcal Infections
      • Risk factors for staphylococcal infections
      • General references
      • Diseases Caused by Staphylococci
        • Staphylococcal bacteremia
        • Staphylococcal skin infections
        • Staphylococcal neonatal infections
        • Staphylococcal pneumonia
        • Staphylococcal endocarditis
        • Staphylococcal osteomyelitis
        • Staphylococcal infectious arthritis
        • Staphylococcal toxic shock syndrome
        • Staphylococcal scalded skin syndrome
        • Staphylococcal food poisoning
        • Diseases caused by staphylococci references
      • Diagnosis
        • MRSA surveillance in health care institutions
        • Diagnosis references
      • Treatment
        • Antibiotic resistance
        • Treatment references
      • Prevention
        • Decolonization of MRSA carriers
        • Prevention references
      • Key Points
    • Streptococcal Infections
      • Classification of Streptococci
      • Virulence Factors
      • Diseases Caused by Streptococci
        • Streptococcal pharyngitis
        • Scarlet fever
        • Streptococcal skin infections
        • Necrotizing fasciitis
        • Streptococcal toxic shock syndrome
        • Delayed complications of streptococcal infection
        • Diseases caused by streptococci references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Pharyngitis
        • Skin infection
        • Other streptococcal infections
        • Treatment references
      • Key Points
    • Toxic Shock Syndrome (TSS)
      • Staphylococcal toxic shock
      • Streptococcal toxic shock
      • General references
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Differential diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Key Points
    • Enterococcal Infections
      • General reference
      • Diagnosis
      • Treatment
        • Resistance
        • Treatment references
    Gram-Positive Bacilli
    • Anthrax
      • Etiology
        • Etiology references
      • Pathophysiology
        • Virulence factors
        • Pathophysiology references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Antibiotics
        • Other medications
        • Drug resistance
        • Pleural fluid drainage
        • Treatment references
      • Prognosis
        • Prognosis references
      • Prevention
        • Postexposure prophylaxis
        • Prevention references
      • Key Points
    • Diphtheria
      • Diphtheria toxin
      • Transmission
      • General references
      • Symptoms and Signs
        • Pharyngeal infection
        • Skin infection
        • Complications
        • Symptoms and signs references
      • Diagnosis
      • Treatment
        • Diphtheria antitoxin
        • Antibiotics
        • Other treatments
        • Treatment references
      • Prevention
        • Vaccination
        • Postexposure antibiotics
        • Prevention reference
      • Key Points
    • Erysipeloid
      • Pathophysiology
        • Pathophysiology references
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Key Points
    • Listeriosis
      • Transmission
      • Risk factors
      • General references
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Nocardiosis
      • Risk factors
      • General reference
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Prognosis
        • Prognosis references
      • Key Points
    Herpesviruses
    • Overview of Herpesvirus Infections
      • General reference
      • Pharmacologic Treatment of Herpesviruses
    • Chickenpox
      • General references
      • Symptoms and Signs
        • Initial rash
        • Breakthrough varicella
        • Complications
        • Symptoms and signs references
      • Diagnosis
      • Treatment
        • Antivirals and chickenpox
        • Treatment reference
      • Prognosis
        • Prognosis references
      • Prevention
        • Vaccination
        • Postexposure prophylaxis
        • Prevention reference
      • Key Points
    • Cytomegalovirus (CMV) Infection
      • General references
      • Symptoms and Signs
      • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • CMV retinitis
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
    • Herpes Simplex Virus (HSV) Infections
      • General references
      • Diseases Caused by Herpes Simplex Virus
        • Mucocutaneous herpes simplex infection
        • Herpes simplex keratitis
        • Herpetic whitlow
        • Herpes simplex CNS infection
        • Neonatal herpes simplex
        • Etiology of herpes simplex virus references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Mucocutaneous herpes simplex infection
        • Herpes simplex keratitis
        • Neonatal herpes simplex
        • Herpes simplex CNS infection
        • Treatment references
      • Key Points
    • Herpes Zoster
      • General references
      • Symptoms and Signs
      • Postherpetic neuralgia
      • Symptoms and signs references
      • Diagnosis
      • Treatment
        • Antiviral therapy
        • Management of postherpetic neuralgia
        • Treatment references
      • Prevention
        • Prevention references
      • Key Points
    • Infectious Mononucleosis
      • General references
      • Pathophysiology
        • Transmission
        • Associated disorders
        • Pathophysiology references
      • Symptoms and Signs
        • Differential diagnosis
        • Complications
        • Symptoms and signs references
      • Diagnosis
        • Laboratory tests
        • Diagnosis references
      • Treatment
      • Prognosis
      • Key Points
    • Genital Herpes
      • General references
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnoses reference
      • Treatment
        • Treatment reference
      • Prevention
        • Preventing neonatal HSV infection
        • Prevention references
      • Key Points
      • More Information
    Human Immunodeficiency Virus (HIV)
    • Human Immunodeficiency Virus (HIV) Infection
      • General reference
      • Epidemiology
        • Epidemiology references
      • Transmission
        • Sexual transmission of HIV
        • Needle- and instrument-related transmission
        • Vertical (mother-to-child) transmission
        • Transfusion- and transplant-related transmission
        • Transmission references
      • Pathophysiology
        • Immune system
        • Other tissues
        • Disease progression
        • Pathophysiology references
      • Symptoms and Signs
        • Initial HIV infection
        • Worsening HIV infection
        • Acquired immune deficiency syndrome (AIDS)
        • Symptoms and signs reference
      • Diagnosis
        • Diagnostic tests
        • Staging
        • Monitoring
        • Diagnosis of HIV-related conditions
        • Diagnosis reference
      • Screening for HIV
      • Treatment
        • Antiretroviral therapy: General principles
        • Immune reconstitution inflammatory syndrome (IRIS)
        • Interruption of antiretroviral therapy
        • Prevention of opportunistic infections
        • Immunization
        • Treatment references
      • Prognosis
        • End-of-life care
      • Prognosis references
      • Prevention
        • Prevention of transmission
        • Postexposure prophylaxis (PEP)
        • Prevention references
      • Key Points
      • More Information
    • Cancers Common in Patients With HIV Infection
      • Non-Hodgkin lymphoma
      • Primary central nervous system lymphoma
      • Cervical cancer
      • Squamous cell carcinoma of the anus or vulva
      • Reference
    • Antiretroviral Treatment of HIV Infection
      • Classes of antiretrovirals
      • Antiretroviral regimens
      • Intramuscular injectable long-acting medications
      • Drug interactions
      • Adverse effects of antiretrovirals
      • Immune reconstitution inflammatory syndrome (IRIS)
      • Interruption of antiretroviral therapy
      • More Information
    Intestinal Protozoa and Microsporidia
    • Overview of Intestinal Protozoan and Microsporidia Infections
      • Diagnosis
    • Amebiasis
      • References
      • Pathophysiology
      • Symptoms and Signs
        • Amebic dysentery
        • Chronic amebic infection of the colon
        • Hepatic or other extraintestinal amebic disease
      • Diagnosis
        • Amebic intestinal infection
        • Amebic liver infection
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
      • More Information
    • Cryptosporidiosis
      • Pathophysiology
        • Pathophysiology reference
      • Epidemiology
        • Epidemiology references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
      • More Information
    • Cyclosporiasis
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • More Information
    • Giardiasis
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
    • Microsporidiosis
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Cystoisosporiasis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • More Information
    Mycobacteria
    • Tuberculosis (TB)
      • General reference
      • Epidemiology
        • Global TB rates
        • United States TB rates
        • Epidemiology of drug-resistant TB
        • Epidemiology references
      • Etiology
        • Etiology references
      • Pathophysiology
        • Primary TB infection
        • Latent TB infection
        • Active TB disease
        • Pathophysiology references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Chest radiography
        • Sputum testing
        • Drug susceptibility tests
        • Tests of other specimens
        • Skin testing
        • IGRA (interferon-gamma release assay)
        • Diagnosis references
      • Treatment
        • Outpatient management
        • Hospitalization
        • Public health considerations
        • Initiating treatment
        • First-line medications for TB
        • Second-line medications for TB
        • Drug resistance
        • Treatment regimens
        • Other treatments
        • Treatment references
      • Prognosis
        • Prognosis references
      • Screening for and Treatment of Latent TB Infection
        • Booster reaction
        • Treatment of LTBI
        • Screening and treatment of latent TB infection references
      • Prevention
        • Vaccination
        • Prevention references
      • Special Populations
        • Patients with HIV infection
        • Children
        • Older adults
        • Special populations references
      • Key Points
    • Nontuberculous Mycobacterial Infections
      • General references
      • Pulmonary Disease
        • Pulmonary disease references
      • Lymphadenitis
        • Lymphadenitis reference
      • Cutaneous Disease
        • Cutaneous infection references
      • Wound and Foreign Body Infections
        • Wound and foreign body infections references
      • Disseminated Disease
        • Disseminated disease reference
    • Leprosy
      • Epidemiology
        • Epidemiology references
      • Pathophysiology
        • Classification of leprosy
        • Pathophysiology references
      • Symptoms and Signs
        • Complications of leprosy
        • Leprosy reactions
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Medications for leprosy
        • Multibacillary leprosy
        • Paucibacillary leprosy
        • Leprosy reactions
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
    • Extrapulmonary Tuberculosis (TB)
      • Pleural TB (TB empyema)
      • Pericardial TB (TB pericarditis)
      • Tuberculous lymphadenitis (scrofula)
      • Miliary TB
      • Meningeal TB (TB meningitis)
      • Gastrointestinal TB
      • Hepatic TB
      • Genitourinary TB
      • Peritoneal TB (TB peritonitis)
      • Cutaneous TB
      • Musculoskeletal TB
      • Other sites of TB infection
      • General references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Key Points
    Nematodes (Roundworms)
    • Angiostrongyliasis
      • General references
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Anisakiasis
      • Reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Ascariasis
      • General references
      • Pathophysiology
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    • Dracunculiasis
      • General reference
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
    • Hookworm Infection
      • General references
      • Pathophysiology
        • Zoonotic (animal) hookworm infections
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Intestinal hookworm infection
        • Cutaneous larva migrans
      • Prevention
      • Key Points
    • Pinworm Infestation
      • General reference
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
    • Strongyloidiasis
      • General references
      • Pathophysiology
        • Autoinfection
        • Hyperinfection syndrome and disseminated strongyloidiasis
      • Symptoms and Signs
        • Hyperinfection syndrome and disseminated strongyloidiasis
      • Diagnosis
        • Screening for strongyloidiasis
      • Treatment
        • Prevention of hyperinfection syndrome and disseminated strongyloidiasis
        • Treatment references
      • Prevention
      • Key Points
    • Toxocariasis
      • General references
      • Pathophysiology
      • Symptoms and Signs
        • Visceral larva migrans
        • Ocular larva migrans
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    • Trichinosis
      • General references
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
    • Trichuriasis
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Overview of Filarial Nematode Infections
    • Bancroftian Lymphatic Filariasis and Brugian Lymphatic Filariasis
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment of acute lymphatic filariasis
        • Treatment of chronic lymphedema
        • Treatment of tropical pulmonary eosinophilia
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
      • More Information
    • Dirofilariasis
    • Loiasis
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment of light infection
        • Treatment of heavy infection
        • Treatment of coinfection
        • Treatment references
      • Prevention
      • Key Points
    • Mansonellosis
      • Mansonella perstans
      • Mansonella ozzardi
      • Mansonella streptocerca
      • References
      • Key Points
    • Onchocerciasis (River Blindness)
      • General reference
      • Pathophysiology
      • Symptoms and Signs
        • Nodules
        • Skin disease
        • Eye disease
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
        • Prevention reference
      • Key Points
    • Baylisascariasis
      • General reference
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    Pox Viruses
    • Mpox (Monkeypox)
      • References
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
        • Vaccination
        • Infection control
        • Prevention reference
      • More Information
    • Smallpox
      • Pathophysiology
      • Symptoms and Signs
        • Variola major
        • Variola minor
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
        • Live vaccinia virus vaccine complications
        • Postexposure prophylaxis
        • Prevention references
      • Key Points
      • More Information
    Respiratory Viruses
    • Overview of Viral Respiratory Infections
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
    • Adenovirus Infections
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    • Common Cold
      • Reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Influenza
      • Influenza antigens
      • Epidemiology
        • High-risk groups
        • Epidemiology reference
      • Symptoms and Signs
        • Complications
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Medications for influenza
        • Treatment references
      • Prognosis
        • Prognosis references
      • Prevention
        • Influenza vaccines
        • Antiviral medications
      • Key Points
    • Parainfluenza Virus Infections
    • Coronaviruses and Acute Respiratory Syndromes (MERS and SARS)
      • Middle East Respiratory Syndrome (MERS)
        • Transmission of MERS-CoV
        • References
        • Symptoms and Signs
        • Diagnosis
        • Treatment
      • Severe Acute Respiratory Syndrome (SARS)
      • SARS references
    • Avian Influenza
      • General references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
      • Key Points
    Rickettsiae and Related Organisms
    • Overview of Rickettsial and Related Infections
      • Symptoms and Signs
      • Diagnosis
        • Differentiating rickettsial from other infections
        • Differentiating among rickettsial diseases
        • Testing
      • Treatment
        • Treatment reference
      • Key Points
    • Other Spotted Fever Rickettsioses
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
    • Epidemic Typhus
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
      • Brill-Zinsser Disease
    • Murine (Endemic) Typhus
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Rickettsialpox
    • Rocky Mountain Spotted Fever (RMSF)
      • Epidemiology
      • Pathophysiology
        • Pathophysiology reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
      • More Information
    • Scrub Typhus
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Ehrlichiosis and Anaplasmosis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
      • More Information
    • Q Fever
      • Etiology
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    Sexually Transmitted Infections (STIs)
    • Overview of Sexually Transmitted Infections
      • General references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
        • Doxycycline postexposure prophylaxis (doxyPEP)
        • Prevention references
    • Chancroid
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
    • Urogenital Chlamydial Infections
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Screening
        • Screening references
      • Treatment
        • Treatment references
      • Key Points
    • Human Papillomavirus (HPV) Infection
      • General references
      • Etiology
        • Etiology reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Prevention
        • Prevention references
      • Key Points
    • Gonorrhea
      • General references
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        • Symptoms and signs references
      • Diagnosis
        • Men with urethritis
        • Women with cervicitis or pelvic inflammatory disease
        • Pharyngeal or rectal exposures
        • Arthritis, disseminated gonococcal infection (DGI), or both
        • Diagnosis reference
      • Screening
        • Screening references
      • Treatment
        • Sex partners
        • Treatment references
      • Key Points
    • Granuloma Inguinale
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
    • Lymphogranuloma Venereum (LGV)
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
    • Sexually Transmitted Enteric Infections
      • References
    • Syphilis
      • General references
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        • Primary syphilis
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        • Latent period
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        • Other lesions
        • Symptoms and signs reference
      • Diagnosis
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        • Latent syphilis
        • Late or tertiary syphilis
        • Diagnosis references
      • Treatment
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        • Jarisch-Herxheimer reaction (JHR)
        • Posttreatment surveillance
        • Treatment references
      • Key Points
    • Trichomoniasis
      • General references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Tests for women
        • Tests for men
        • Tests for both sexes
      • Treatment
        • Treatment references
      • Key Points
    • Urogenital Mycoplasmal Infections
      • General references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
    Spirochetes
    • Bejel, Pinta, and Yaws
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Key Points
    • Leptospirosis
      • General reference
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
      • Treatment
        • Treatment references
      • Prevention
      • Key Points
    • Lyme Disease
      • General reference
      • Epidemiology
        • Epidemiology reference
      • Pathophysiology
      • Symptoms and Signs
        • Early-localized stage
        • Early-disseminated stage
        • Late-stage disease
        • Symptoms and signs references
      • Diagnosis
        • Differential diagnosis
        • Diagnosis references
      • Treatment
      • Prevention
        • Prevention references
      • Key Points
    • Rat-Bite Fever
      • Streptobacillary rat-bite fever
      • Spirillary rat-bite fever (sodoku)
      • General reference
      • Diagnosis
        • Confirmation of streptobacillary rat-bite fever
        • Confirmation of spirillary rat-bite fever
      • Treatment
      • Prognosis
        • Prognosis reference
    • Relapsing Fever
      • General references
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Prognosis
        • Prognosis reference
      • Key Points
    Trematodes (Flukes)
    • Introduction to Trematodes (Flukes)
    • Clonorchiasis
      • General references
      • Pathophysiology
        • Pathophysiology reference
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
    • Fascioliasis
      • General reference
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
    • Fasciolopsiasis
      • References
    • Heterophyiasis and Related Trematode Infections
      • References
    • Opisthorchiasis
      • References
    • Paragonimiasis
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • References
    • Schistosomiasis
      • Etiology
        • Etiology references
      • Pathophysiology
      • Symptoms and Signs
        • Acute schistosome dermatitis
        • Acute schistosomiasis
        • Chronic schistosomiasis
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Prevention
        • Prevention references
      • Key Points
      • Dermatitis Caused by Avian and Animal Schistosomes
    Urinary Tract Infections
    • Introduction to Urinary Tract Infections
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    • Bacterial Urinary Tract Infections
      • General references
      • Pathophysiology
        • Risk factors
        • Pathophysiology references
      • Etiology
        • Etiology references
      • Classification
        • Acute cystitis
        • Acute pyelonephritis
        • Asymptomatic bacteriuria
        • Acute urethral syndrome
        • Classification references
      • Symptoms and Signs
      • Diagnosis
        • Urine collection
        • Urine testing
        • Infection localization
        • Other testing
        • Diagnosis references
      • Treatment
        • Cystitis
        • Acute pyelonephritis
        • Asymptomatic bacteriuria
        • Acute urethral syndrome
        • Treatment references
      • Prevention
        • Prevention references
      • Key Points
    • Fungal Urinary Tract Infections
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Key Points
    • Catheter-Associated Urinary Tract Infections
      • General references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prevention
        • Prevention references
      • Key Points
    • Reflux Nephropathy (Chronic Pyelonephritis)
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Prognosis
        • Prognosis reference
      • Key Points
    Viruses
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      • Viruses and cancer
      • References
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        • Prevention reference
    • Target Organs of Viral Infections
      • Viral respiratory infections
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      • Viral hepatitis
      • Viral neurologic infections
      • Hemorrhagic fevers
      • Cutaneous or mucosal infections
      • Multisystem diseases
      • Nonspecific febrile illness
      • References
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