Biology of Infectious Disease

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• Introduction to the Biology of Infectious Diseases
  • Reference

• Host Defense Mechanisms Against Infection
  • Natural Barriers Against Infection
    • Skin
    • Mucous membranes
    • Respiratory tract
    • Gastrointestinal tract
    • Genitourinary tract
    • Natural barriers reference
  • Nonspecific Immune Responses (Innate Immune Responses)
  • Specific Immune Responses (Adaptive Immune Responses)
  • Host Genetic Factors

• Factors Facilitating Microbial Invasion
  • Virulence Factors
    • Capsule
    • Enzymes
    • Toxins
    • Other factors
  • Microbial Adherence
    • Biofilm
  • Antimicrobial Resistance
    • Reference
  • Defects in Host Defense Mechanisms
    • Mechanisms

• Manifestations of Infection
  • Clinical manifestations
  • Hematologic manifestations
  • Other organ systems
  • Reference

• Fever
  • Pathophysiology
    • Consequences of fever
  • Etiology
    • Infectious causes
  • Evaluation
    • History
    • Physical examination
    • Red flags
    • Interpretation of findings
    • Testing
  • Treatment
    • Treatment reference
  • Geriatrics Essentials
    • Reference
  • Key Points

• Fever of Unknown Origin (FUO)
  • General reference
  • Etiology
    • Etiology reference
  • Evaluation
    • History
    • History reference
    • Physical examination
    • Red flags
    • Interpretation of findings
    • Testing
    • Testing reference
  • Treatment
  • Geriatrics Essentials
  • Key Points

• Abscesses
  • Etiology
  • Symptoms and Signs
  • Diagnosis
  • Treatment
    • Treatment reference
  • Key Points

• Bacteremia
  • Etiology
  • Pathophysiology
  • Symptoms and Signs
  • Diagnosis
  • Treatment
    • Treatment references
  • Key Points