honeypot link
skip to main content
  • follow us on facebook
  • follow us on X
MSD Manual LogoMSD ManualConsumer Version
HEALTH TOPICSHEALTHY LIVINGSYMPTOMSEMERGENCIESRESOURCESCOMMENTARYABOUT US
homeHEALTH TOPICSHEALTHY LIVING
Search icon
  1. <Health Topics
    Mental Health
    Overview of Mental Health Care
    • Personality and Behavior Changes
      • Confusion and delirium
      • Delusions
      • Disorganized speech
      • Disorganized behavior
      • Hallucinations
      • Mood extremes
      • Causes
        • Mental illnesses
        • Medications and illicit/recreational drugs
        • Disorders that mainly affect the brain
        • Bodywide disorders that also affect the brain
      • Evaluation
        • Warning signs
        • When to see a doctor
        • What the doctor does
        • Testing
      • Treatment
      • Key Points
    • Overview of Mental Illness
      • Causes
      • Diagnosis
        • Classification of mental illness
      • Social Support
      • Deinstitutionalization
      • More Information
    • Treatment of Mental Illness
      • Medication Therapy
      • Psychotherapy
        • Behavioral therapy
        • Cognitive therapy
        • Interpersonal therapy
        • Psychoanalysis
        • Psychodynamic psychotherapy
        • Supportive psychotherapy
      • Electroconvulsive Therapy
        • Other brain stimulation therapies
    Anxiety and Stressor-Related Disorders
    • Social Anxiety Disorder
      • Diagnosis
      • Treatment
      • More Information
    • Agoraphobia
      • Diagnosis
      • Treatment
      • More Information
    • Overview of Trauma- and Stressor-Related Disorders
      • More Information
    • Acute Stress Disorder
      • Diagnosis
      • Treatment
        • Self-care
        • Psychotherapy
        • Medications
    • Adjustment Disorders
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Self-care
        • Psychotherapy
        • Medications
    • Posttraumatic Stress Disorder (PTSD)
      • Symptoms
        • Intrusion symptoms
        • Avoidance symptoms
        • Negative effects on thinking and mood
        • Changes in alertness and reactions
        • Other symptoms
      • Diagnosis
      • Treatment
        • Self-care
        • Psychotherapy
        • Medications
      • More Information
    • Overview of Anxiety Disorders
      • Causes
      • Anxiety caused by a medical condition or medication
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    • Generalized Anxiety Disorder
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    • Panic Attacks and Panic Disorder
      • Symptoms
      • Diagnosis
      • Treatment
        • Medications
        • Psychotherapy
      • More Information
    • Specific Phobias
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    Dissociative Disorders
    • Overview of Dissociative Disorders
    • Depersonalization/Derealization Disorder
      • Causes
      • Symptoms
      • Diagnosis
      • Treatment
      • Prognosis
    • Dissociative Amnesia
      • Symptoms
      • Diagnosis
      • Treatment
        • Supportive environment
        • Memory-retrieval techniques
        • Psychotherapy
      • Prognosis
      • Dissociative Fugue
        • Treatment of Dissociative Fugue
    • Dissociative Identity Disorder
      • Causes
      • Symptoms
        • More than one identity
        • Amnesia
        • Other symptoms
      • Diagnosis
      • Treatment
      • Prognosis
    • Dissociative Subtype of Posttraumatic Stress Disorder
      • Symptoms
      • Diagnosis
      • Treatment
      • Prognosis
    Feeding and Eating Disorders
    • Avoidant/Restrictive Food Intake Disorder (ARFID)
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    • Pica
      • Diagnosis
      • Treatment
      • More Information
    • Rumination Disorder
      • Diagnosis
      • Treatment
      • More Information
    • Overview of Feeding and Eating Disorders
      • Causes
      • More Information
    • Anorexia Nervosa
      • Risk Factors
      • Symptoms
      • Diagnosis
      • Treatment
      • Prognosis
      • More Information
    • Bulimia Nervosa
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    • Binge-Eating Disorder
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    Mood Disorders
    • Medications for Treatment of Depression
      • Antidepressants and Suicide Risk
      • Classes of Antidepressant Medications
        • Selective serotonin reuptake inhibitors (SSRIs)
        • Serotonin modulators, serotonin-norepinephrine reuptake inhibitors, and norepinephrine-dopamine reuptake inhibitors
        • N-methyl D-aspartate (NMDA) antagonist/sigma-1 agonist
        • Heterocyclic (including tricyclic) antidepressants
        • Monoamine oxidase inhibitors (MAOIs)
        • Melatonergic antidepressant
        • Ketamine and esketamine
    • Medications for Treatment of Bipolar Disorders
      • Mood Stabilizers
        • Lithium
        • Antiseizure medications
        • Antipsychotics
        • Antidepressants
      • Precautions During Pregnancy
        • Antiseizure medications
        • Lithium
        • Antipsychotics
        • Antidepressants
      • More Information
    • Overview of Mood Disorders
      • Symptoms and Episodes
        • Depression
        • Mania
        • Hypomania
        • Mixed features
      • Complications of Mood Disorders
        • Suicide in mood disorders
        • Other complications of mood disorders
      • More Information
    • Depression
      • Causes and Risk Factors
      • Symptoms
        • Major depressive disorder
        • Persistent depressive disorder
        • Premenstrual dysphoric disorder
        • Prolonged grief disorder
        • Substance use
        • Other effects of depression
      • Screening
      • Diagnosis
        • Testing
      • Treatment
        • Support
        • Psychotherapy
        • Medications for depression
        • Electroconvulsive therapy
        • Phototherapy (light therapy)
        • Other therapies
      • More Information
    • Bipolar Disorders
      • Causes
      • Symptoms
      • Diagnosis
      • Treatment
        • Psychotherapy
        • Education and support
        • Other treatments
      • More Information
    • Cyclothymic Disorder
      • Treatment
      • More Information
    Obsessive-Compulsive and Related Disorders
    • Hair-Pulling Disorder (Trichotillomania)
      • Symptoms
      • Diagnosis
      • Treatment
    • Skin-Picking (Excoriation) Disorder
      • Symptoms
      • Diagnosis
      • Treatment
    • Body Dysmorphic Disorder (BDD)
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    • Hoarding Disorder
      • Symptoms
      • Diagnosis
      • Treatment
    • Olfactory Reference Disorder
    • Body-Focused Repetitive Behavior Disorder
      • Symptoms
      • Diagnosis
      • Treatment
    • Obsessive-Compulsive Disorder (OCD)
      • Symptoms
      • Diagnosis
      • Treatment
    Paraphilias and Paraphilic Disorders
    • Overview of Paraphilias and Paraphilic Disorders
    • Exhibitionistic Disorder
      • Diagnosis
      • Treatment
    • Fetishistic Disorder
      • Treatment
    • Pedophilic Disorder
      • Diagnosis
      • Treatment
      • Medications
    • Sexual Masochism Disorder
      • Asphyxiophilia (autoerotic asphyxiation)
    • Sexual Sadism Disorder
    • Transvestic Disorder
      • Diagnosis
      • Treatment
    • Voyeuristic Disorder
      • Diagnosis
      • Treatment
    • Frotteuristic Disorder
      • Diagnosis
      • Treatment
    Personality Disorders
    • Antisocial Personality Disorder
      • Causes
      • Symptoms
        • Disregard for others
        • Impulsive behavior (impulsivity)
        • Irresponsibility
        • Other symptoms
      • Diagnosis
      • Treatment
    • Avoidant Personality Disorder
      • Causes
      • Symptoms
        • Fear of rejection
        • Extreme sensitivity to criticism
        • Other symptoms
      • Diagnosis
      • Treatment
    • Borderline Personality Disorder (BPD)
      • Causes
      • Symptoms
        • Fear of abandonment
        • Anger
        • Changeability
        • Impulsive behavior and self-harm
        • Other symptoms
      • Diagnosis
      • Treatment
        • Psychotherapy
        • Medications
      • Prognosis
    • Dependent Personality Disorder
      • Causes
      • Symptoms
        • Need for care
        • Excessive submissiveness
        • Lack of confidence
        • Lack of independence
      • Diagnosis
      • Treatment
    • Histrionic Personality Disorder
      • Symptoms
        • Need for attention
        • Problems with emotions
        • Other symptoms
      • Diagnosis
      • Treatment
    • Narcissistic Personality Disorder
      • Causes
      • Symptoms
        • Grandiosity
        • Fantasies of specialness
        • Need for admiration
      • Diagnosis
      • Treatment
    • Obsessive-Compulsive Personality Disorder
      • Symptoms
        • Focus on order and perfectionism
        • Effects on work
        • Effects on other aspects of life
        • Other symptoms
      • Diagnosis
      • Treatment
    • Paranoid Personality Disorder
      • Symptoms
        • Interpretation of experiences as hostile
        • Effect on relationships
      • Diagnosis
      • Treatment
    • Schizoid Personality Disorder
      • Causes
      • Symptoms
        • Detachment from others
        • Limited expression of emotions
        • Persistence of symptoms
      • Diagnosis
      • Treatment
    • Schizotypal Personality Disorder
      • Causes
      • Symptoms
        • Effect on relationships
        • Odd thinking and behavior
        • Perception of reality
      • Diagnosis
      • Treatment
    • Overview of Personality Disorders
      • Causes
      • Types of Personality Disorders
      • Symptoms
      • Diagnosis
      • Treatment
        • General principles of treatment
      • More Information
    Schizophrenia and Related Disorders
    • Other Schizophrenia Spectrum and Psychotic Disorders
      • Shared Delusions
    • Introduction to Schizophrenia and Related Disorders
    • Brief Psychotic Disorder
    • Delusional Disorder
      • Symptoms
        • Types of delusional disorder
      • Diagnosis
      • Treatment
      • Prognosis
    • Psychotic Disorder Due to Another Medical Condition
    • Schizoaffective Disorder
      • Treatment
    • Antipsychotic Medications
      • How Antipsychotic Medications Work
      • Types of Antipsychotic Medications
      • Side Effects of Antipsychotic Medications
    • Schizophreniform Disorder
    • Substance- or Medication-Induced Psychotic Disorder
      • Treatment
    • Schizophrenia
      • Causes
      • Symptoms
        • Positive symptoms
        • Disorganization
        • Negative symptoms
        • Cognitive impairment
        • Suicide
        • Violence
      • Diagnosis
      • Treatment
        • Antipsychotic medications
        • Rehabilitation programs and community support activities
        • Psychotherapy
      • Prognosis
      • More Information
    Gender Incongruence and Gender Dysphoria
    • Gender Incongruence and Gender Dysphoria
      • Symptoms
        • Gender incongruence and gender dysphoria symptoms in adults
        • Gender incongruence and gender dysphoria symptoms in children
      • Diagnosis
      • Treatment
        • Gender-affirming hormone therapy
        • Gender-affirming surgery
      • More Information
    Somatic Symptom and Related Disorders
    • Functional Neurological Symptom Disorder
      • Symptoms
      • Diagnosis
      • Treatment
      • More Information
    • Factitious Disorder Imposed on Self
      • Symptoms
      • Diagnosis
      • Treatment
    • Illness Anxiety Disorder
      • Symptoms
      • Diagnosis
      • Treatment
    • Psychological Factors Affecting Other Medical Conditions
    • Somatic Symptom Disorder
      • Symptoms
      • Diagnosis
      • Treatment
    • Factitious Disorder Imposed on Another
    • Overview of Somatic Symptom and Related Disorders
    Substance-Related Disorders
    • Substance-Related Mental Health Disorders
    • Substance Use Disorders
      • Physiologic Effects of Substance Use
      • Intoxication
      • Withdrawal
      • Causes
        • Drug
        • User
        • Setting
      • Diagnosis
        • Criteria for diagnosis
      • Treatment
      • Screening
      • Prevention
    • Overview of Substance-Related Disorders
      • Scheduled Drugs (Controlled Substances)
    Suicidal Behavior
    • Suicide Prevention
    • Support for those Impacted by Suicide
      • More Information
    • Suicidal Behavior
      • Suicidal behavior rates
      • Methods
      • Causes
        • Antidepressants and the risk of suicide
        • Causes of suicide in adolescents
        • Suicide contagion
      • Treatment
    MSD
    • About
    • Disclaimer
    • Permissions
    • Privacy
    • Cookie Preferences
    • Terms of use
    • Partnerships
    • Contact Us
    • Global Medical Knowledge
    • Veterinary Manual
    • Mobile App
    • follow us on facebook
    • follow us on X
    This icon serves as a link to download the eSSENTIAL Accessibility assistive technology app for individuals with physical disabilities. It is featured as part of our commitment to diversity and inclusion.
    • follow us on facebook
    • follow us on X
    This icon serves as a link to download the eSSENTIAL Accessibility assistive technology app for individuals with physical disabilities. It is featured as part of our commitment to diversity and inclusion.
    MSD

    Copyright© 2026Merck & Co., Inc., Rahway, NJ, USA and its affiliates. All rights reserved.