Causes of Secondary Osteoporosis
Cancer (eg, multiple myeloma) |
COPD (chronic obstructive pulmonary disease) due to the disorder and tobacco use, decreased physical activity, and treatment with glucocorticoids |
Medications and substances (eg, chronic use of glucocorticoids, antiseizure medications, medroxyprogesterone, aromatase inhibitors, rosiglitazone, pioglitazone, thyroid replacement therapy, heparin, ethanol, tobacco, , medroxyprogesterone, aromatase inhibitors, rosiglitazone, pioglitazone, thyroid replacement therapy, heparin, ethanol, tobacco,proton pump inhibitors, H2 blockers) |
Endocrine disease (eg, Cushing syndrome, hyperparathyroidism, hyperthyroidism, hypogonadism, hyperprolactinemia, diabetes mellitus) |
Hypercalciuria |
Hypophosphatemia (chronic) |
Immobilization |
Liver disease |
Prolonged weightlessness (as occurs in space flight) |