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  1. <Medical Topics
    Gynecology and Obstetrics
    Approach to the Gynecologic Patient
    • Obstetric and Gynecologic History
      • Obstetric History
        • Gravidity and parity
        • Obstetric outcomes and complications
        • Obstetric history references
      • Gynecologic History
    • Well-Woman Visits
      • Pelvic Examination
      • Breast Examination
      • Psychosocial Screening and Counseling
      • References
    • Pelvic Examination
      • Reference
      • Pelvic Examination Procedure
        • External examination
        • Speculum examination
        • Bimanual examination
        • Rectovaginal examination
    • Gynecologic Evaluation in Children and Adolescents
      • Children
      • Adolescents
      • References
    • Gynecologic Diagnostic Tests and Procedures
      • Pregnancy Testing
        • Pregnancy testing reference
      • Testing for Infection
        • Testing for vaginitis
        • Testing for sexually transmitted infections
      • Cervical Cancer Testing
        • Cervical cancer screening
        • Cervical diagnostic and treatment procedures
        • Cervical testing references
      • Other Gynecologic Biopsies
        • Vulvar biopsy
        • Vaginal biopsy
        • Endometrial biopsy
        • Other gynecologic biopsies references
      • Imaging Studies
      • Diagnostic Procedures
        • Dilation and curettage
        • Hysteroscopy
        • Laparoscopy
        • Culdocentesis
    Symptoms of Gynecologic Disorders
    • Female Pelvic Pain
      • Reference
      • Etiology
        • Gynecologic disorders
        • Nongynecologic disorders
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
        • Treatment reference
      • Geriatrics Essentials
      • Key Points
    • Vaginal Bleeding
      • Etiology
        • Etiology references
      • Pathophysiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Evaluation references
      • Treatment
      • Geriatrics Essentials
      • Key Points
    • Vulvovaginal Pruritus or Vaginal Discharge
      • Pathophysiology
      • Etiology
        • Reproductive-aged women
        • Postmenopausal women
        • Women of all ages
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Evaluation reference
      • Treatment
        • Treatment reference
      • Geriatrics Essentials
      • Key Points
    • Female Pelvic Mass
      • Etiology
      • Evaluation
        • History
        • Examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Evaluation references
      • Treatment
        • Treatment reference
      • Key Points
    • Female Pelvic Mass in Children
      • Etiology
        • Etiology references
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
        • Treatment references
      • Key Points
    • Vaginal Bleeding in Children
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Evaluation reference
      • Treatment
        • Treatment reference
      • Key Points
    • Vulvovaginal Pruritus or Vaginal Discharge in Children
      • Etiology
        • Etiology reference
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Evaluation reference
      • Treatment
      • Key Points
    Breast Disorders
    • Breast Masses (Breast Lumps)
      • Etiology
        • Etiology reference
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
        • Treatment reference
      • Key Points
    • Nipple Discharge
      • Pathophysiology
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
      • Key Points
    • Mastalgia (Breast Pain)
      • Etiology
        • Etiology reference
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
      • Key Points
    • Evaluation of Breast Disorders
      • Evaluation
        • History
        • Breast examination
        • Red flags
        • Testing
        • Evaluation reference
    Endometriosis
    • Vulvar Endometriomas
      • Reference
    • Endometriosis
      • References
      • Etiology and Pathophysiology
        • Etiology and pathophysiology references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Pharmacologic therapy
        • Surgery
        • Treatment reference
      • Key Points
    Family Planning
    • Overview of Contraception
      • References
    • Permanent Contraception
      • Vasectomy
      • Tubal Sterilization
        • Permanent contraception by laparoscopy
        • Permanent contraception by minilaparotomy
        • Permanent contraception by hysteroscopy
        • Complications
        • References
        • Key Points
    • Procedural and Medical Abortion
      • References
      • Methods
        • Procedural abortion
        • Medical abortion
        • Methods references
      • Complications
      • Key Points
    • Oral Contraceptives
      • Estrogen-progestin oral contraceptives
        • Contraindications to estrogen-progestin contraceptives (pills, patch, vaginal ring)
      • Progestin-only oral contraceptives
        • Contraindications to progestin-only contraceptives (pills, implants, injections)
      • General reference
      • Adverse Effects
        • Adverse effects references
      • Benefits
        • Benefits reference
      • Drug Interactions
        • Drug interactions references
      • Initiation
        • Late or missed doses of oral contraceptives
        • Postpartum use of oral contraceptives
        • Initiation reference
      • Key Points
    • Transdermal and Vaginal Ring Hormonal Contraceptives
      • Transdermal contraceptives
      • Vaginal ring contraceptives
      • General reference
    • Progestin Contraceptive Injections
      • Contraindications and adverse effects
      • Benefits
      • References
    • Subdermal Contraceptive Implants
      • Reference
    • Barrier and Other Pericoital Contraceptives
      • Condoms
      • Diaphragm
      • Cervical cap
      • Contraceptive sponge
      • Spermicides
      • pH regulator contraceptive gel
      • References
    • Intrauterine Device (IUDs; IUD)
      • Insertion of the IUD
      • Contraindications
      • Adverse effects
      • Potential benefits
      • Complications
      • References
      • Key Points
    • Fertility Awareness‒Based Methods of Contraception
      • Standard days method
      • Two-day method
      • Symptothermal method
      • Lactational amenorrhea method
    • Emergency Contraception
      • References
      • Key Points
    Female Reproductive Endocrinology
    • Female Reproductive Endocrinology
      • Puberty
        • Age of onset of puberty
        • Physical changes of puberty
        • Mechanisms initiating puberty
        • Puberty references
      • Ovarian Follicular Development
        • Ovarian follicular development references
      • Menstrual Cycle
        • Follicular phase
        • Ovulatory phase
        • Luteal phase
      • Menstrual cycle references
      • Cyclic Changes in Other Reproductive Organs
        • Endometrium
        • Cervix
        • Vagina
    Infertility and Recurrent Pregnancy Loss
    • Sperm Disorders
      • Pathophysiology
      • Etiology
        • Impaired spermatogenesis
        • Impaired sperm emission
        • Other causes
      • Diagnosis
      • Semen analysis
      • Genetic testing
      • Other tests
      • Treatment
      • Key Points
    • Abnormal Cervical Mucus
      • Diagnosis
      • Treatment
      • Key Points
    • Diminished Ovarian Reserve
      • Diagnosis
      • Treatment
      • Key Points
    • Ovulatory Dysfunction
      • Etiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Letrozole
        • Clomiphene
        • Metformin
        • Exogenous gonadotropins
        • Treatment of the underlying disorder
        • Treatment references
      • Key Points
    • Tubal Dysfunction and Pelvic Abnormalities
      • Etiology
      • Diagnosis
      • Treatment
    • Unexplained Infertility
      • Treatment
      • Prognosis
        • Prognosis reference
    • Assisted Reproductive Technologies
      • In vitro fertilization (IVF)
      • Intracytoplasmic sperm injection (ICSI)
      • Other technologies
      • General references
    • Recurrent Pregnancy Loss
      • Etiology
        • Etiology reference
      • Diagnosis
      • Treatment
        • Treatment references
      • Key Points
    • Overview of Infertility
      • General references
      • Evaluation
      • Treatment
      • More Information
    Menopause
    • Menopause
      • General references
      • Physiology
      • Symptoms and Signs
        • Vasomotor
        • Vaginal
        • Neuropsychiatric
        • Cardiovascular
        • Musculoskeletal
        • Other symptoms
        • Symptoms and signs references
      • Diagnosis
      • Treatment
        • Nonpharmacologic measures
        • Hormone therapy
        • Selective estrogen receptor modulators (SERMs)
        • Nonhormonal medications
        • Herbal or dietary supplements
        • Treatment references
      • Menopausal Hormone Therapy
        • Choice of systemic hormone therapy
        • Genitourinary syndrome of menopause treatment
        • Osteoporosis management
        • Risks and adverse effects
        • Hormone therapy references
      • Key Points
      • Additional Information
    Abnormal Uterine Bleeding
    • Introduction to Abnormal Uterine Bleeding
    • Amenorrhea
      • General references
      • Pathophysiology
      • Etiology
        • Amenorrhea due to ovulatory dysfunction
        • Amenorrhea due to structural reproductive tract abnormalities
        • Etiology references
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Evaluation references
      • Treatment
      • Guidelines
      • Key Points
    • Abnormal Uterine Bleeding
      • Pathophysiology
        • Complications
      • Etiology
        • Etiology references
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Laboratory testing
        • Imaging studies
        • Endometrial sampling
        • Diagnosis references
      • Treatment
        • Medications
        • Procedures
        • Management of acute uterine bleeding
        • Treatment references
      • Guidelines
      • Key Points
    • Dysmenorrhea
      • General references
      • Etiology
        • Primary dysmenorrhea
        • Secondary dysmenorrhea
        • Etiology references
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Evaluation reference
      • Treatment
        • General measures
        • Medications
        • Other treatments
        • Treatment references
      • Guidelines
      • Key Points
    • Polycystic Ovary Syndrome (PCOS)
      • General reference
      • Pathophysiology
        • Pathophysiology references
      • Complications
        • Complications references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosing PCOS in adolescent girls
        • Diagnosis references
      • Treatment
        • Management of hirsutism
        • Management of infertility
        • Management of comorbidities
        • Treatment references
      • Guidelines
      • Key Points
      • More Information
    • Primary Ovarian Insufficiency
      • Etiology
        • Etiology references
      • Symptoms and Signs
      • Diagnosis
        • Diagnostic references
      • Treatment
        • Treatment references
      • Guidelines
      • Key Points
    • Premenstrual Syndrome (PMS)
      • References
      • Etiology
        • Etiology references
      • Symptoms and Signs
        • Premenstrual dysphoric disorder (PMDD)
      • Diagnosis
      • Treatment
        • General measures
        • Medications
        • Surgery
        • Treatment references
      • Guidelines
      • Key Points
    • Pelvic Venous Disorders
      • General reference
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Guidelines
      • Key Points
    Miscellaneous Gynecologic Disorders
    • Adnexal Torsion
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Guidelines
      • Key Points
    • Bartholin Gland Cyst and Bartholin Gland Abscess
      • General references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Benign Adnexal Masses
      • Types of Adnexal Masses
        • Functional ovarian cysts
        • Benign ovarian neoplasms
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Guidelines for Benign Adnexal Masses
      • Key Points
    • Cervical Polyps
      • Reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Key Points
    • Cervical Stenosis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Key Points
    • Skene Gland Cyst
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Vulvar Inclusion and Epidermal Cysts
      • Diagnosis
        • Diagnosis reference
      • Treatment
    • Uterine Adenomyosis
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Key Points
    Pelvic Organ Prolapse (POP)
    • Overview of Pelvic Organ Prolapse (POP)
      • Risk Factors
      • Staging
      • References
    • Anterior and Posterior Vaginal Wall Prolapse
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Pelvic floor muscle exercises
        • Pessaries
        • Surgical repair
        • References
      • Key Points
    • Uterine and Apical Prolapse
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Uterine prolapse
        • Vaginal apical prolapse
        • Reference
      • Key Points
    Female Sexual Function and Dysfunction
    • Overview of Female Sexual Function and Dysfunction
      • References
      • Physiology
        • Desire (libido)
        • Arousal
        • Orgasm
        • Resolution
      • Classification
        • Classification reference
      • Etiology
        • Primarily psychological factors
        • Primarily physical factors
        • Etiology reference
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Psychological therapies
        • Pharmacologic therapy
        • Other therapies
        • Treatment references
      • Key Points
    • Female Orgasmic Disorder
      • Etiology
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Key Points
    • Persistent Genital Arousal Disorder
      • Treatment
    • Genito-Pelvic Pain/Penetration Disorder
      • Etiology
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Key Points
    • Pregnancy-Related and Postpartum Sexual Dysfunction
    • Sexual Interest/Arousal Disorder
      • Etiology
      • Diagnosis
      • Treatment
        • Estrogen therapy
        • Testosterone therapy
        • Other therapies
        • Treatment references
    Uterine Fibroids
    • Uterine Fibroids
      • References
      • Symptoms and Signs
        • Symptoms and signs references
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Medications to treat fibroids
        • Procedures to treat fibroids
        • Surgery for fibroids
        • Choice of treatment
        • Treatment references
      • Key Points
    • Fibroids in Pregnancy
      • Reference
    • Cervical Leiomyomas
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    Vaginitis, Cervicitis, and Pelvic Inflammatory Disease
    • Overview of Vaginitis
      • Etiology
        • Children
        • Women of reproductive age
        • Women who are postmenopausal
        • Women of all ages
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Key Points
    • Pelvic Inflammatory Disease (PID)
      • Etiology
        • Risk factors
      • Symptoms and Signs
        • Cervicitis
        • Acute salpingitis
        • Complications
      • Diagnosis
        • Differential diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Bacterial Vaginosis (BV)
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment references
      • Key Points
    • Candidal Vaginitis
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
    • Inflammatory Vaginitis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
    • Cervicitis
      • Etiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Key Points
    Prenatal Genetic Counseling and Evaluation
    • Prenatal Genetic Counseling
      • Risk Factors for Genetic Disorders or Congenital Anomalies
      • Risk factors for congenital disorders references
    • Preconception or Prenatal Carrier Testing of Parents
      • General references
      • Prenatal Testing to Detect Fetal Genetic Abnormalities
        • Testing references
    • Noninvasive Prenatal Fetal Screening Tests
      • Screening in multiple gestations
      • First-Trimester Screening
        • Cell-free fetal nucleic acid testing
        • First-trimester screening references
      • Second-Trimester Screening
        • Maternal serum screening for chromosomal abnormalities
        • Maternal serum screening for neural tube defects
        • Second-trimester screening references
      • Sequential First- and Second-Trimester Screening
        • Sequential first- and second trimester screening references
      • Prenatal Ultrasonography
    • Procedures for Prenatal Genetic Diagnosis
      • Preimplantation Genetic Testing (PGT)
      • Chorionic Villus Sampling
      • Amniocentesis
      • Percutaneous Umbilical Blood Sampling
      • References
    Approach to the Pregnant Woman and Prenatal Care
    • Fertilization and Development of the Embryo
      • Amniotic sac and placenta
      • Embryo
    • Physiology of Pregnancy
      • Physiology
        • Cardiovascular
        • Hematologic
        • Urinary
        • Respiratory
        • Gastrointestinal (GI) and hepatobiliary
        • Endocrine
        • Dermatologic
    • Anemia in Pregnancy
      • References
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Key Points
      • Iron Deficiency Anemia in Pregnancy
        • Diagnosis
        • Treatment
        • Prevention
      • Folate Deficiency Anemia in Pregnancy
        • Diagnosis
        • Treatment
        • Prevention
      • Hemoglobinopathies in Pregnancy
        • Hemoglobinopathies references
    • Infectious Disease in Pregnancy
      • Antimicrobials
      • References
      • Key Points
    • Thromboembolic Disorders in Pregnancy
      • Reference
      • Diagnosis
      • Treatment
      • Key Points
    • Urinary Tract Infection in Pregnancy
      • References
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Key Points
    • Multifetal Gestation
      • Complications
      • References
      • Diagnosis
      • Management
      • Key Points
    • Late-Term and Postterm Pregnancy
      • Reference
      • Management
      • Key Points
    • Evaluation of the Obstetric Patient
      • General reference
      • History
        • Gravidity and parity
      • Physical Examination
        • Physical examination reference
      • Symptoms and Signs
      • Diagnosis
      • Estimated Date of Delivery
      • Testing
        • Laboratory testing
        • Ultrasonography
        • Other imaging
        • Testing references
      • Management
        • Symptoms requiring evaluation
        • Diet and supplements
      • Weight gain
      • Physical activity
      • Medications, substance use, and toxic exposures
      • Immunizations
      • Prevention of perinatal complications
      • Psychosocial issues
      • Travel
      • Treatment references
    Symptoms During Pregnancy
    • Pelvic Pain During Early Pregnancy
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
      • Key Points
    • Vaginal Bleeding During Early Pregnancy
      • General references
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
        • Diagnosis references
      • Treatment
      • Key Points
    • Nausea and Vomiting During Early Pregnancy
      • General reference
      • Pathophysiology
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
        • Treatment references
      • Key Points
    • Lower-Extremity Edema During Late Pregnancy
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
      • Key Points
    • Vaginal Bleeding During Late Pregnancy
      • Pathophysiology
      • Etiology
      • Evaluation
        • History
        • Physical examination
        • Red flags
        • Interpretation of findings
        • Testing
      • Treatment
      • Key Points
    Intrapartum Complications
    • Intraamniotic Infection
      • Risk factors
      • Complications
      • Symptoms and Signs
      • Diagnosis
        • Subclinical infection
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    • Placenta Accreta
      • General reference
      • Etiology
        • Etiology references
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
      • Key Points
    • Amniotic Fluid Embolism
      • General references
      • Pathophysiology
        • Risk factors
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Shoulder Dystocia
      • General reference
      • Risk Factors
      • Symptoms and Signs
      • Diagnosis
      • Management
        • Management references
      • Key Points
    • Uterine Inversion
      • Diagnosis
      • Treatment
    • Postpartum Hemorrhage
      • Etiology
      • Diagnosis
        • Diagnosis references
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    • Umbilical Cord Prolapse
      • Occult prolapse
      • Overt prolapse
    • Uterine Rupture
      • Etiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
    • Introduction to Intrapartum Complications
    • Fetal Presentation, Position, and Lie (Including Breech Presentation)
      • Transverse lie
      • Breech presentation
      • Face or brow presentation
      • Occiput posterior position
      • Key Points
    Antenatal Complications
    • Overview of High-Risk Pregnancy
      • General reference
    • Risk Factors for Pregnancy Complications
      • Diabetes
        • Diabetes references
      • Hypertension
        • Hypertension references
      • Thyroid Disorders
      • Sexually Transmitted Infections (STIs)
        • STIs references
      • Female Genital Tract Abnormalities
      • Substance Use
      • Exposure to Teratogens
      • Exposure to Mercury
      • Maternal Age
        • Maternal age reference
      • Maternal Weight
        • Maternal weight references
      • Multiple Gestation
        • Multiple gestation reference
      • Prior Neonate With a Genetic or Congenital Disorder
      • Prior Stillbirth
        • Prior stillbirth references
      • Prior Preterm Delivery
        • Prior preterm delivery reference
      • Prior Birth Injury
    • Placental Abruption (Abruptio Placentae)
      • Risk factors
      • Complications
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Cervical Insufficiency
      • Etiology
        • Risk factors
        • Recurrence
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Key Points
    • Hemolytic Disease of the Fetus and Neonate
      • Pathophysiology
      • Diagnosis
      • Treatment
      • Prevention
        • Prevention references
      • Key Points
    • Pemphigoid Gestationis
      • Reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Key Points
    • Placenta Previa
      • Risk factors
      • Complications
      • General references
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment references
      • Key Points
    • Preeclampsia and Eclampsia
      • General references
      • Etiology
        • Etiology references
      • Pathophysiology
        • Complications
        • Pathophysiology references
      • Symptoms and Signs
      • Diagnosis
        • Evaluation
        • Other hypertensive disorders in pregnancy
        • Diagnosis references
      • Treatment
        • General approach
        • Monitoring
        • Magnesium sulfate
        • Supportive treatments
        • Delivery method
        • Follow-up
        • Postpartum preeclampsia
        • Treatment reference
      • Prevention
        • Prevention references
      • Key Points
    • Polymorphic Eruption of Pregnancy
      • Reference
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Key Points
    • Stillbirth
      • General reference
      • Etiology
        • Complications
      • Diagnosis
      • Diagnosis reference
      • Treatment
      • Key Points
    • Vasa Previa
      • General reference
      • Symptoms and Signs
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment reference
      • Key Points
    • Maternal Mortality and Perinatal Mortality
      • Maternal and perinatal mortality references
    • Prelabor Rupture of Membranes (PROM)
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Expectant management
        • Treatment reference
      • Key Points
    • Preterm Labor
      • Diagnosis
      • Treatment
        • Antibiotics
        • Tocolytics
        • Magnesium sulfate
        • Corticosteroids
        • Progestins
        • Treatment references
      • Key Points
    • Hyperemesis Gravidarum
      • Diagnosis
        • Differential diagnosis
      • Treatment
        • Treatment reference
      • Key Points
    • Polyhydramnios
      • Complications
      • Symptoms and Signs
      • Diagnosis
        • Identification of cause
        • Diagnosis references
      • Treatment
        • Treament reference
      • Key Points
    • Oligohydramnios
      • Complications
      • Symptoms and Signs
      • Diagnosis
        • Identification of cause
        • Diagnosis references
      • Treatment
        • Treatment references
      • Key Points
    Drug Safety in Pregnancy
    • Drug Safety in Pregnancy
      • Regulatory Information about Drug Safety During Pregnancy
      • Drug Transfer and Metabolism During Pregnancy
      • Vaccines During Pregnancy
      • Antivirals During Pregnancy
      • Antidepressants During Pregnancy
      • References
      • More Information
    • Social and Illicit Drugs During Pregnancy
    Early Pregnancy Disorders
    • Ectopic Pregnancy
      • General reference
      • Etiology
        • Etiology reference
      • Pathophysiology
        • Pathophysiology reference
      • Symptoms and Signs
      • Diagnosis
        • Differential diagnosis
      • Diagnosis reference
      • Treatment
        • Methotrexate
        • Surgical resection
        • Treatment reference
      • Prognosis
        • Prognosis reference
      • Key Points
    • Spontaneous Abortion
      • General references
      • Etiology
        • Etiology reference
      • Symptoms and Signs
        • Symptoms and signs reference
      • Diagnosis
        • Differential diagnosis
        • Diagnosis reference
      • Treatment
        • Treatment references
      • Key Points
    • Septic Abortion
      • Symptoms and Signs
      • Diagnosis
      • Treatment
      • Key Points
    Labor and Delivery
    • Management of Normal Labor
      • General reference
      • Birthing Options
      • Beginning of Labor
      • Admission to Labor Unit
      • Cervical Examination
      • Rupture of Membranes
        • Rupture of membranes references
      • Stages of Labor
        • First stage
        • Second stage
        • Third stage
      • Stages of labor references
    • Management of Spontaneous Vaginal Delivery
      • Delivery of the Fetus
        • Delivery of the fetus references
      • Delivery of the Placenta
      • Immediate Postpartum Care
    • Protracted or Arrested Labor
      • General reference
      • Etiology
      • Diagnosis
        • Diagnosis references
      • Treatment
      • Treatment reference
      • Key Points
    • Operative Vaginal Delivery
      • General references
    • Induction of Labor
      • Indications
        • Indications reference
      • Technique
      • Technique reference
    • Cesarean Delivery
      • Indications
        • Indications reference
      • Technique
      • Post-Delivery Care
    • Fetal Monitoring During Labor and Delivery
      • Fetal Monitoring Methods
        • Fetal monitoring methods reference
      • Fetal Heart Rate Monitoring Interpretation
        • Fetal monitoring interpretation reference
      • Fetal Assessment Tests
    • Analgesia and Anesthesia for Labor and Delivery
      • General reference
      • Neuraxial Anesthesia
        • Epidural anesthesia
        • Spinal anesthesia
        • Neuraxial anesthesia reference
      • Locoregional Analgesia
        • Locoregional analgesia reference
      • Parenteral Analgesia
      • General Anesthesia
      • Postpartum Pain Management
        • Postpartum pain management references
    Postpartum Care and Associated Disorders
    • Mastitis
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
    • Postpartum Endometritis
      • References
      • Risk Factors
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
      • Key Points
    • Postpartum Pyelonephritis
      • Diagnosis
      • Treatment
        • Treatment reference
    • Postpartum Depression
      • General reference
      • Symptoms and Signs
      • Diagnosis
      • Diagnosis references
      • Treatment
        • Treatment of postpartum depression references
      • Key Points
    • Postpartum Care
      • Postpartum Physiologic Changes
        • Clinical parameters
        • Laboratory parameters
      • Routine Postpartum Care
        • Perineal care
        • Cesarean wound care
        • Pain management
        • Bladder and bowel function
        • Diet and exercise
        • Breast engorgement
        • Sexual activity
        • Contraception
        • Routine postpartum care references
      • Postpartum Preventive Care
        • Prevention of Rh sensitization
        • Vaccination
        • Postpartum preventive care references
      • Postpartum Complications
        • Hemorrhage
        • Hypertensive disorders
        • Infection
        • Thromboembolic disorders
        • Headache after neuraxial anesthesia (spinal headache)
        • Perineal repair complications
        • Psychiatric disorders
        • Postpartum complications references
    Pregnancy Complicated by Disease
    • Asthma in Pregnancy
      • General reference
      • Treatment
        • Treatment references
    • Autoimmune Disorders in Pregnancy
      • Systemic Lupus Erythematosus in Pregnancy
        • Reference
      • Antiphospholipid Syndrome in Pregnancy
        • Diagnosis
        • Treatment
      • Immune Thrombocytopenia in Pregnancy
        • References
      • Rheumatoid Arthritis in Pregnancy
        • Reference
      • Myasthenia Gravis in Pregnancy
        • Reference
    • Cancer in Pregnancy
      • Breast cancer
      • Cervical cancer
      • Other gynecologic cancers
      • Rectal cancer
      • Leukemia and Hodgkin lymphoma
      • References
    • Diabetes Mellitus in Pregnancy
      • Risks of diabetes during pregnancy
      • General references
      • Diagnosis
        • Diagnosis reference
      • Treatment
        • During pregnancy
        • Management of complications
        • Labor and delivery
        • Postpartum
        • Treatment references
      • Key Points
    • Heart Disease in Pregnancy
      • General reference
      • Pathophysiology
      • Symptoms and Signs
      • Diagnosis
      • Treatment
        • Arrhythmias
        • Endocarditis prophylaxis
      • Key Points
      • Valvular Stenosis and Insufficiency in Pregnancy
        • Treatment
      • Other Heart Disorders in Pregnancy
        • Mitral valve prolapse
        • Congenital heart disease
        • Peripartum cardiomyopathy
        • General reference
    • Hepatic Disorders in Pregnancy
      • Jaundice
      • Acute viral hepatitis
      • Chronic hepatitis
      • Intrahepatic cholestasis (pruritus) of pregnancy
      • Fatty liver of pregnancy
      • Preeclampsia
      • Chronic hepatic disorders
      • General reference
      • Key Points
    • Hypertension in Pregnancy
      • General reference
      • Diagnosis
      • Treatment
        • Pharmacologic treatment
        • Treatment reference
      • Key Points
    • Renal Insufficiency in Pregnancy
      • End-stage renal disease
      • Key Points
    • Seizure Disorders in Pregnancy
      • Reference
    • Disorders Requiring Surgery During Pregnancy
      • Appendicitis
      • Benign ovarian cysts
      • Gallbladder disease
      • Intestinal obstruction
    • Thyroid Disorders in Pregnancy
      • Graves disease
      • Congenital Graves disease
      • Maternal hypothyroidism
      • Hashimoto thyroiditis
      • Acute (subacute) thyroiditis
      • Postpartum maternal thyroid dysfunction
    • COVID-19 During Pregnancy
      • General references
      • Diagnosis
      • Treatment
        • Treatment reference
      • Prevention
        • COVID-19 vaccine
        • Breastfeeding
        • Prevention references
      • Key Points
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