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Causes of Secondary Raynaud Syndrome

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Cause	Examples
Autoimmune and inflammatory disorders	Mixed or undifferentiated connective tissue disease Idiopathic inflammatory myopathies (such as polymyositis or dermatomyositis) Rheumatoid arthritis Sjögren syndrome Systemic lupus erythematosus Systemic sclerosis
Hormonal disorders	Hypothyroidism
Blood disorders	Cold agglutinin disease Polycythemia vera
Cancer and related disorders	Gastrointestinal neuroendocrine tumors Paraneoplastic syndrome
Nerve disorders	Carpal tunnel syndrome
Trauma	Frostbite Vibration
Blood vessel disorders	Thoracic outlet syndrome
Medications and substances	Beta-blockers Cocaine Ergot preparations (used for migraines and to control bleeding after childbirth) Nicotine Stimulant medications