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Medical Topics
Allergy and Immunology
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Biology of the Immune System
Molecular Components of the Immune System
Acute Phase Reactants
Acute phase reactants references
Antibodies
Antibody structure
Antibody classes
Antibodies references
Cytokines
Chemokines
Colony-stimulating factors
Interferons (IFNs)
Interleukins (ILs)
Transforming growth factors (TGF)
Tumor necrosis factors (TNFs)
Cytokines references
Overview of the Immune System
Innate immunity
Acquired immunity
General references
Immune Response
Activation
Regulation
Resolution
Immune response references
Geriatrics Essentials
Geriatrics essentials references
Cellular Components of the Immune System
Antigen-Presenting Cells
Antigen-presenting cells references
Lymphocytes
B cells
T cells
Lymphocytes references
Mast Cells
Mast cells references
Natural Killer (NK) Cells
Natural killer cells references
Polymorphonuclear Leukocytes
Neutrophils
Eosinophils
Basophils
Polymorphonuclear leukocytes references
Human Leukocyte Antigen (HLA) System
References
Complement System
Complement activation
Complement deficiencies and defects
Biologic activities of complement
References
Immunotherapeutics
Monoclonal antibodies
Fusion proteins
Soluble cytokine receptors
Recombinant cytokines
Small-molecule mimetics
Cellular therapies
References
Allergic, Autoimmune, and Other Hypersensitivity Disorders
Allergic Rhinitis
Symptoms and Signs
Diagnosis
Diagnosis reference
Treatment
Prevention
Avoidance of triggers
Desensitization
Key Points
Food Allergy
General reference
Etiology
Oral allergy syndrome (pollen food allergy syndrome)
Eosinophilic gastroenteropathy
Alpha-gal syndrome
Etiology references
Symptoms and Signs
Diagnosis
Treatment
Immunotherapy for desensitization
Monoclonal antibodies
Treatment references
Prevention
Prevention references
Key Points
More Information
Anaphylaxis
General reference
Etiology
Pathophysiology
Anaphylactoid reactions
Symptoms and Signs
Diagnosis
Treatment
Epinephrine
Other treatments
Treatment references
Prevention
Key Points
Angioedema
Acute angioedema
Chronic angioedema
Hereditary and acquired angioedema
References
Symptoms and Signs
Diagnosis
Treatment
Key Points
Hereditary and Acquired
C1 Inhibitor
Deficiency or Dysfunction
Hereditary angioedema
Acquired C1 inhibitor deficiency
Triggers
General reference
Symptoms and Signs
Diagnosis
Diagnosis reference
Treatment
Treatment references
Prevention
Long-term prophylaxis
Short-term prophylaxis
Prevention references
Key Points
Overview of Allergic and Atopic Disorders
Classification of Hypersensitivity Reactions
Type I hypersensitivity reactions
Type II hypersensitivity reactions
Type III hypersensitivity reactions
Type IV hypersensitivity reactions
Etiology
Allergens
Pathophysiology
Symptoms and Signs
Diagnosis
Nonspecific tests
Specific tests
Diagnosis reference
Treatment
Emergency treatment
Environmental control
Antihistamines
Mast cell stabilizers
Anti-inflammatory medications
Other medications
Immunotherapy
Allergy treatment during pregnancy and breastfeeding
Treatment references
Prevention
Key Points
More Information
Autoimmune Disorders
Mechanisms
Genetic factors
Defense mechanisms
Reference
Drug Hypersensitivity
Pathophysiology
Pathophysiology references
Symptoms and Signs
Diagnosis
Skin testing
Other testing
Diagnosis references
Treatment
Desensitization
Treatment references
Prognosis
Prognosis reference
Key Points
Mastocytosis and Mast Cell Activation Syndrome
Classification
Cutaneous mastocytosis
Systemic mastocytosis
Mast cell activation syndrome
Classification reference
Symptoms and Signs
Diagnosis
Systemic mastocytosis
Mast cell activation syndrome
Diagnosis references
Treatment
Cutaneous mastocytosis
Systemic mastocytosis
Mast cell activation syndrome
Treatment references
Key Points
Immunodeficiency Disorders
Selective Antibody Deficiency With Normal Immunoglobulins (SADNI)
General reference
Diagnosis
Diagnosis reference
Treatment
Overview of Immunodeficiency Disorders
Primary Immunodeficiencies
Humoral immunity deficiencies
Cellular immunity deficiencies
Combined humoral and cellular immunity deficiencies
Phagocytic cell defects
Complement deficiencies
Primary immunodeficiency references
Secondary Immunodeficiencies
Geriatrics Essentials
Key Points
Approach to the Patient With Suspected Immunodeficiency
Manifestations of immunodeficiency
Evaluation
History
Physical examination
Initial testing
Additional testing
Prenatal and neonatal diagnosis
Evaluation references
Treatment
Infection prevention
Management of acute infection
Replacement of missing immune components
Investigational therapy
Treatment references
Prognosis
Key Points
Ataxia-Telangiectasia
General reference
Symptoms and Signs
Diagnosis
Diagnosis references
Treatment
Treatment references
Key Points
Chédiak-Higashi Syndrome
Symptoms and Signs
Diagnosis
Treatment
Treatment reference
Chronic Granulomatous Disease (CGD)
Symptoms and Signs
Symptoms and signs reference
Diagnosis
Treatment
Treatment references
Key Points
Chronic Mucocutaneous Candidiasis
Symptoms and Signs
Diagnosis
Treatment
Key Points
Common Variable Immunodeficiency (CVID)
Symptoms and Signs
Diagnosis
Treatment
Treatment reference
DiGeorge Syndrome
Symptoms and Signs
Diagnosis
Treatment
Treatment reference
Hyper-IgE Syndrome
Symptoms and Signs
Diagnosis
Treatment
Treatment reference
Hyper-IgM Syndrome
X-linked hyper-IgM syndrome
Autosomal recessive hyper-IgM syndrome
Diagnosis
Treatment
Treatment reference
Selective IgA Deficiency
General references
Symptoms and Signs
Diagnosis
Diagnosis reference
Treatment
Prognosis
Key Points
Leukocyte Adhesion Deficiency
Symptoms and Signs
Diagnosis
Treatment
Treatment reference
Severe Combined Immunodeficiency (SCID)
Symptoms and Signs
Diagnosis
Diagnosis reference
Treatment
Treatment references
Key Points
Transient Hypogammaglobulinemia of Infancy
Wiskott-Aldrich Syndrome
General reference
Symptoms and Signs
Diagnosis
Treatment
Treatment references
X-linked Agammaglobulinemia
Diagnosis
Treatment
Treatment references
X-linked Lymphoproliferative Syndrome
Symptoms and Signs
Diagnosis
Treatment
Treatment references
ZAP-70 Deficiency
Diagnosis
Treatment
