Вибрані стани, асоційовані з клостридіальними інфекціями
Condition | Agent | Toxin |
|---|---|---|
Soft-tissue infection | ||
Crepitant cellulitis, myositis, clostridial myonecrosis, hemolysis | C. perfringens, others | Alpha-toxin (phospholipase C), theta-toxin, others |
Gas gangrene, tissue necrosis, hemolysis | C. septicum | Alpha-toxin, beta-toxin, hyaluronidase gamma-toxin, septicolysin delta-toxin |
Enteric diseases | ||
C. perfringens type A | Enterotoxin | |
Clostridial necrotizing enteritis (enteritis necroticans; pigbel) | C. perfringens type C | Beta-toxin |
Clostridioides difficile (formerly Clostridium difficile) | Toxin A or B or C. difficile binary toxin (CDT) | |
C. septicum, others | Unknown, possibly beta-toxin | |
C. septicum | — | |
Abdominal infections: Cholecystitis, peritonitis, ruptured appendix, bowel perforation | C. perfringens, C. ramosum, many others | Beta-toxin* |
Neurologic syndromes | ||
C. tetani | Tetanospasmin | |
C. botulinum | Botulinal toxins A–G and F/A Hybrid | |
* Beta-toxin is produced by C. perfringens type C, but most of these infections are caused by C. perfringens type A, which does not produce beta-toxin. | ||