• Bacterial infections, multiple or recurrent*

• Candidiasis of bronchi, trachea, or lungs

• Candidiasis of esophagus

• Cervical cancer, invasive†

• Coccidioidomycosis, disseminated or extrapulmonary

• Cryptococcosis, extrapulmonary

• Cryptosporidiosis, chronic intestinal (lasting > 1 month)

• Cytomegalovirus disease (other than liver, spleen, or lymph nodes), onset at age > 1 month

• Cytomegalovirus retinitis (with loss of vision)

• Encephalopathy attributed to HIV

• Herpes simplex: chronic ulcers (lasting > 1 month) or bronchitis, pneumonitis, or esophagitis (onset at age > 1 month)

• Histoplasmosis, disseminated or extrapulmonary

• Isosporiasis (cystoisosporiasis), chronic intestinal (lasting > 1 month)

• Kaposi sarcoma

• Lymphoma, Burkitt (or equivalent term)

• Lymphoma, immunoblastic (or equivalent term)

• Lymphoma, primary, of brain

• Mycobacterium avium complex (MAC) or Mycobacterium kansasii, disseminated or extrapulmonary

• Mycobacterium tuberculosis of any site, pulmonary, disseminated, or extrapulmonary

• Mycobacterium, other species or unidentified species, disseminated or extrapulmonary

• Pneumocystis jirovecii (previously known as Pneumocystis carinii) pneumonia

• Pneumonia, recurrent†

• Progressive multifocal leukoencephalopathy

• Salmonella septicemia (nontyphoid), recurrent

• Toxoplasmosis of brain, onset at age > 1 month

• Wasting syndrome attributed to HIV

See also Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report (MMWR):Revised Surveillance Case Definition for HIV Infection, United States, 2014.

* Only among children aged < 6 years

† Only among adults, adolescents, and children aged ≥ 6 years