Гістологія слизової тонкої кишки при деяких порушеннях мальабсорбції
Disorder | Histologic Characteristics |
|---|---|
Normal | Fingerlike villi with a villous:crypt ratio of about 4:1 Columnar epithelial cells with numerous regular microvilli (brush border) Mild round cell infiltration in the lamina propria |
Celiac disease (untreated) | Virtual absence of villi and elongated crypts Increased intraepithelial lymphocytes and round cells (especially plasma cells) in the lamina propria Cuboidal epithelial cells with scanty, irregular microvilli |
Dilation and ectasia of the intramucosal lymphatics | |
Range from minimal changes in villous height and moderate epithelial cell damage to virtual absence of villi and elongated crypts with lymphocyte infiltration in the lamina propria | |
Lamina propria densely infiltrated with periodic acid-Schiff–positive macrophages Villous structure possibly obliterated in severe lesions |