[{"Title":"Довідковий матеріал загального характеру","UniqueID":"v88073248_uk","Index":1.0,"Summary":"

1. Husebye ES, Pearce SH, Krone NP, Kämpe O. Adrenal insufficiency. Lancet. 2021;397(10274):613-629. doi:10.1016/S0140-6736(21)00136-7Adr

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Етіологія","UniqueID":"v982295_uk","Index":2.0,"Summary":"

Approximately 90% of cases of primary adrenal insufficiency in the United States and Europe are due to autoimmune disease ( 1 ). The remainder result from destruction of the adrenal gland by granuloma (eg, tuberculosis , histoplasmosis ), tumor, amyloidosis , hemorrhage, or inflammatory necrosis. Hypoadrenocorticism can also result from administration of medications that block glucocorticoid synthesis (eg, ketoconazole, etomidate).

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"cause\" itemscope itemtype=\"http://schema.org/MedicalCause\"","Children":[{"Title":"Довідковий матеріал щодо етіології","UniqueID":"v88073257_uk","Index":1.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"cause\" itemscope itemtype=\"http://schema.org/MedicalCause\"","Children":[]}]},{"Title":"Патофізіологія","UniqueID":"v982300_uk","Index":3.0,"Summary":"

In adrenal insufficiency, both mineralocorticoids and glucocorticoids are deficient.

","HeadType":"F_Head","SchemeItemProp":"","Children":[{"Title":"Мінералокортикоїдний дефіцит","UniqueID":"v982303_uk","Index":1.0,"Summary":"

In adrenal insufficiency, both mineralocorticoids and glucocorticoids are deficient.

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Дефіцит глюкокортикоїдів","UniqueID":"v982308_uk","Index":2.0,"Summary":"

In adrenal insufficiency, both mineralocorticoids and glucocorticoids are deficient.

","HeadType":"G_Head","SchemeItemProp":"","Children":[]}]},{"Title":"Симптоми та ознаки","UniqueID":"v982314_uk","Index":4.0,"Summary":"

Weakness, fatigue, and orthostatic hypotension are early symptoms and signs of Addison disease.

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[{"Title":"Криз надниркових залоз","UniqueID":"v982320_uk","Index":1.0,"Summary":"

Weakness, fatigue, and orthostatic hypotension are early symptoms and signs of Addison disease.

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]}]},{"Title":"Діагностика","UniqueID":"v982325_uk","Index":5.0,"Summary":"

Electrolyte levels

","HeadType":"F_Head","SchemeItemProp":"","Children":[{"Title":"Диференційний діагноз","UniqueID":"v982429_uk","Index":1.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Дослідження","UniqueID":"v982440_uk","Index":2.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Провокаційна проба","UniqueID":"v26440905_uk","Index":3.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Тестування для визначення етіології","UniqueID":"v26440958_uk","Index":4.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Довідковий матеріал щодо діагностики","UniqueID":"v105414004_uk","Index":5.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]}]},{"Title":"Лікування","UniqueID":"v982457_uk","Index":6.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[{"Title":"Лікування кризу надниркових залоз","UniqueID":"v982473_uk","Index":1.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]},{"Title":"Лікування ускладнень","UniqueID":"v982481_uk","Index":2.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]},{"Title":"Довідковий матеріал щодо лікування","UniqueID":"v105414013_uk","Index":3.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]}]},{"Title":"Ключові моменти","UniqueID":"v6576215_uk","Index":7.0,"Summary":"

Addison disease is primary adrenal insufficiency.

","HeadType":"F_Head","SchemeItemProp":"","Children":[]}]