Risk Factors for Liver Disorders

Risk Factors for Liver Disorders

Category

Risk Factors

Acquired

Alcohol use

Blood transfusions (particularly before 1992)*

Body piercing*

Medications (prescription and nonprescription), illicit substances, and herbal product use

Exposure to other liver toxins

Exposure to hepatitis*

Fontan palliation for hypoplastic left heart syndrome or other single ventricle heart disease

High-risk sexual practices*†

Needlesticks*

Parenteral or intranasal illicit drug use*

Shellfish ingestion

Tattoos*

Familial

Family history of disorders such as primary biliary cholangitis, hemochromatosis, Wilson disease, alpha-1 antitrypsin deficiency, and hepatitis B (which can be vertically transmitted)

Inflammatory bowel disease

* These factors increase risk of hepatitis in particular.

† High-risk sexual practices include: new sexual partner or more than one sexual partner in the last 3 months and engaged in anal sex in the last 3 months; sexual contact with a person who ever had a positive HIV test; sexual contact with a person who used nonprescription injection drugs in the past 3 months or a person who engaged in sex for money or drugs in the past 3 months.

* These factors increase risk of hepatitis in particular.

† High-risk sexual practices include: new sexual partner or more than one sexual partner in the last 3 months and engaged in anal sex in the last 3 months; sexual contact with a person who ever had a positive HIV test; sexual contact with a person who used nonprescription injection drugs in the past 3 months or a person who engaged in sex for money or drugs in the past 3 months.