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Cause	Examples
Extracranial disorders	Carotid or vertebral artery dissection (which also causes neck pain) Dental disorders (eg, infection, temporomandibular joint dysfunction) Glaucoma Sinusitis
Intracranial disorders	Brain tumors and other masses Chiari type I malformation Cerebrospinal fluid leak with low-pressure headache Hemorrhage (intracerebral hemorrhage, subdural hemorrhage, subarachnoid hemorrhage) Idiopathic intracranial hypertension Infections (eg, abscess, encephalitis, meningitis, subdural empyema) Meningitis, noninfectious (eg, carcinomatous, chemical) Obstructive hydrocephalus Vascular disorders (eg, ischemic stroke, hemorrhagic stroke, vascular malformations, vasculitis, venous sinus thrombosis) Cerebral venous sinus thrombosis
Systemic disorders	Acute severe hypertension Bacteremia Fever Giant cell arteritis Hypercapnia Hypoxia (including altitude sickness) Postural orthostatic tachycardia syndrome (POTS) Viral infections
Medications, other substances, and toxins	Analgesic overuse Caffeine withdrawalCaffeine withdrawal Carbon monoxide Hormone therapy (eg, estrogen) Nitrates Proton pump inhibitors