MSD Manual

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Daptomycin

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Medically Reviewed Jun 2022 | Modified Sep 2022
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Topic Resources

Daptomycin works by interfering with the bacteria's cell membrane, which results in rapid death of the bacteria.

Table

Daptomycin

Common Uses

Some Potential Side Effects

Comments

Gastrointestinal upset

Muscle pain and weakness

Not used when infection involves the lungs because daptomycin is made inactive by surfactant (a substance normally produced in the lungs)

Use of Daptomycin During Pregnancy and Breastfeeding

NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
VIEW PROFESSIONAL VERSION
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