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Oxazolidinones: Linezolid and Tedizolid

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Last full review/revision Jun 2022| Content last modified Jun 2022
CLICK HERE FOR THE PROFESSIONAL VERSION
Topic Resources

Oxazolidinones include the following:

  • Linezolid

  • Tedizolid

Oxazolidinones work by preventing bacteria from producing proteins they need to grow and multiply.

Table

Oxazolidinones

Drug

Common Uses

Some Potential Side Effects

Linezolid

Nausea and diarrhea

Headache

Anemia and low white blood cell and platelet counts

Numbness and tingling in the hands and feet (peripheral neuropathy)

Visual disturbances

Serotonin syndrome (confusion, agitation, tremors, or coma) in some people who have growths that sometimes produce excessive amounts of hormone-like substances (such as serotonin) or take selective serotonin-reuptake inhibitors Selective serotonin reuptake inhibitors (SSRIs) Agomelatine, a new type of antidepressant, is a possible treatment for major depressive episodes. Several types of drugs can be used to treat depression: Selective serotonin reuptake inhibitors... read more , monamine oxidase inhibitors, or some other drugs that affect serotonin levels

Tedizolid

Gastrointestinal upset

Headache

Anemia and a low white blood cell count

Use of Linezolid and Tedizolid During Pregnancy and Breastfeeding

NOTE: This is the Consumer Version. DOCTORS: CLICK HERE FOR THE PROFESSIONAL VERSION
CLICK HERE FOR THE PROFESSIONAL VERSION
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