Lefamulin is an antibiotic Overview of Antibiotics Antibiotics are drugs used to treat bacterial infections. They are not effective against viral infections and most other infections. Antibiotics either kill bacteria or stop them from reproducing... read more that works by interfering with the bacteria's production of the proteins it needs to grow and multiply.
Lefamulin is used to treat community-acquired pneumonia Community-Acquired Pneumonia Community-acquired pneumonia is lung infection that develops in people who are not patients in a hospital, usually in people with normal (competent) immune systems, or in those who are immunocompromised... read more that is caused by many bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, Chlamydophila pneumoniae, and Mycoplasma pneumoniae.
Use of Lefamulin During Pregnancy and Breastfeeding
When lefamulin was given to pregnant animals, some harmful effects on the fetus were observed, but no well-designed studies have been done in pregnant women. Pregnant women should be given an alternative drug until better safety data are available. Females of reproductive age should use contraception while taking lefamulin and for 2 days after the last dose. (See also Drug Use During Pregnancy Drug Use During Pregnancy More than 50% of pregnant women take prescription or nonprescription (over-the-counter) drugs or use social drugs (such as tobacco and alcohol) or illicit drugs at some time during pregnancy... read more .)
Women who are breastfeeding should pump and discard breast milk while taking lefamulin and for 2 days after the last dose. (See also Drug Use During Breastfeeding Drug Use During Breastfeeding When mothers who are breastfeeding have to take a drug, they wonder whether they should stop breastfeeding. The answer depends on the following: How much of the drug passes into the milk Whether... read more .)