Oxazolidinones are a class of antibiotics used to treat serious infections, often after other antibiotics have been ineffective.
Oxazolidinones include the following:
Oxazolidinones work by preventing bacteria from producing proteins they need to grow and multiply.
Oxazolidinones
|
Drug |
Common Uses |
Some Side Effects |
|
Linezolid |
Serious infections caused by susceptible gram-positive bacteria such as Staphylococcus (including methicillin-resistant Staphylococcus aureus [MRSA]), Streptococcus, and enterococci (including vancomycin-resistant enterococci) that are resistant to many other antibiotics |
Nausea and diarrhea Headache Anemia and low white blood cell and platelet counts Numbness and tingling in the hands and feet (peripheral neuropathy) Visual disturbances Serotonin syndrome (confusion, agitation, tremors, or coma) in some people who also take selective serotonin-reuptake inhibitors, monamine oxidase inhibitors, and some other drugs that affect serotonin levels. Build up of lactic acid in the blood (lactic acidosis) |
|
Tedizolid |
Complicated skin infections due to susceptible bacteria, including MRSA |
Gastrointestinal upset Headache Anemia and a low white blood cell count |
(See also Overview of Antibiotics.)
Use of Linezolid and Tedizolid During Pregnancy and Breastfeeding
Linezolid and tedizolid should be used during pregnancy only if the benefits exceed the risk. (See also Drug Use During Pregnancy.)
Whether linezolid and tedizolid are safe to use during breastfeeding is unknown. (See also Drug Use During Breastfeeding.)
