Tigecycline works by preventing bacteria from producing proteins they need to grow and multiply.
This drug is effective against many resistant bacteria, including those with resistance to tetracyclines. However, the risk of dying is higher with tigecycline than with other antibiotics. Thus, tigecycline is used only if no alternatives are available. Tigecycline is given intravenously.
(See also Overview of Antibiotics.)
When taken during pregnancy, tigecycline, like tetracyclines, may have harmful effects on tooth and bone development in the fetus, but sometimes the benefits of treatment may outweigh the risks. (See also Drug Use During Pregnancy.)
Whether tigecycline is safe to use during breastfeeding is unknown. (See also Drug Use During Breastfeeding.)