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Lefamulin

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Last full review/revision Jul 2020| Content last modified Jul 2020
Click here for the Professional Version

Lefamulin is an antibiotic that works by interfering with the bacteria's production of the proteins it needs to grow and multiply.

Lefamulin is used to treat community-acquired pneumonia that is caused by many bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, Chlamydophila pneumoniae, and Mycoplasma pneumoniae.

Use of Lefamulin During Pregnancy and Breastfeeding

When lefamulin was given to pregnant animals, some harmful effects on the fetus were observed, and no well-designed studies have been done in pregnant women. Pregnant women should be given an alternative drug until better safety data are available. Females of reproductive age should use contraception while taking lefamulin and for 2 days after the last dose. (See also Drug Use During Pregnancy.)

Women who are breastfeeding should pump and discard breast milk while taking lefamulin and for 2 days after the last dose. (See also Drug Use During Breastfeeding.)

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Test your knowledge

Respiratory Syncytial Virus (RSV) Infection and Human Metapneumovirus Infection
Respiratory syncytial virus (RSV) infection and human metapneumovirus infection (hMVP) cause upper and sometimes lower respiratory tract infections. Symptoms of both viruses are similar although the viruses are different. In which of the following ages groups is RSV a very common cause of respiratory tract infections?
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