Себорейні кератози

ЗаDenise M. Aaron, MD, Dartmouth Geisel School of Medicine
ПереглянутоJoseph F. Merola, MD, MMSc, UT Southwestern Medical Center
Переглянуто/перевірено Змінено серп. 2025
v967772_uk

Seborrheic keratoses are superficial, often pigmented, epithelial lesions that are usually verrucous but may occur as smooth papules and plaques that have a stuck-on appearance.

The cause of seborrheic keratosis is unknown, but genetic mutations have been identified in certain types. The lesions commonly occur in middle age and later and most often appear on the trunk or temples. In patients with dark skin, multiple 1- to 3-mm lesions can occur on the cheekbones; this condition is termed dermatosis papulosa nigra.

Seborrheic keratoses vary in size and grow slowly. They may be round or oval and flesh-colored, brown, or black. They usually have a stuck-on appearance and may have a verrucous, velvety, waxy, scaling, or crusted surface.

Seborrheic keratoses that are large, multiple, and/or rapidly developing can be a cutaneous paraneoplastic syndrome (Leser-Trélat sign) in patients who have certain cancers (eg, lymphoma, gastrointestinal cancer).

Прояви себорейного кератозу
Себорейний кератоз
Себорейний кератоз

Seborrheic keratoses are benign pigmented lesions. Cause is unknown. They tend to develop in older adults and have a stuck-on appearance with a verrucous, velvety, waxy, scaly, or crusted surface.

Seborrheic keratoses are benign pigmented lesions. Cause is unknown. They tend to develop in older adults and have a st

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Image provided by Thomas Habif, MD.

Себорейні кератози (спина)
Себорейні кератози (спина)

This photo shows seborrheic keratoses (hyperpigmented lesions with a stuck-on appearance) on a patient's back.

This photo shows seborrheic keratoses (hyperpigmented lesions with a stuck-on appearance) on a patient's back.

DermPics/SCIENCE PHOTO LIBRARY

Дерматоз папульозний чорний
Дерматоз папульозний чорний

This photo shows multiple, small seborrheic keratoses on the cheekbones and forehead of a person with dark skin.

This photo shows multiple, small seborrheic keratoses on the cheekbones and forehead of a person with dark skin.

DermPics/SCIENCE PHOTO LIBRARY

Дерматоз папульозний чорний (2)
Дерматоз папульозний чорний (2)

This photo depicts several seborrheic keratoses on the cheekbones and infraorbital region in a patient with dark skin.

This photo depicts several seborrheic keratoses on the cheekbones and infraorbital region in a patient with dark skin.

Photo courtesy of Karen McKoy, MD.

Симптом Лезера-Трела
Симптом Лезера-Трела

Leser-Trélat sign is the rapid onset of numerous seborrheic keratoses (benign, often pigmented skin lesions with a "stuck-on" appearance).

Leser-Trélat sign is the rapid onset of numerous seborrheic keratoses (benign, often pigmented skin lesions with a "stu

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© Springer Science+Business Media

Diagnosis of Seborrheic Keratoses

  • History and physical examination alone

Diagnosis of seborrheic keratosis is clinical. Dermoscopy is very helpful in making a definitive diagnosis of seborrheic keratosis.

Treatment of Seborrheic Keratoses

  • Removal only if bothersome

Lesions are not premalignant and do not require treatment unless they are irritated, itchy, or cosmetically bothersome to the patient.

Lesions may be removed with little or no scarring by cryotherapy (which can cause hypopigmentation) or by electrodesiccation and curettage after local injection of lidocaine.