Apoaequorin

NaLaura Shane-McWhorter, PharmD, University of Utah College of Pharmacy
Imekaguliwa naEva M. Vivian, PharmD, MS, PhD, University of Wisconsin School of Pharmacy
Imepitiwa/Imerekebishwa Imebadilishwa Jul 2025
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Apoaequorin is derived from jellyfish called Aequorea victoria. A laboratory-made version of apoaequorin is the main ingredient in the over-the-counter dietary supplement called Prevagen.

Madai ya Apoaekuorini

Apoaequorin is said to improve mild age-related memory loss, possibly by decreases levels of calcium in the brain. Apoaequorin in combination with other active ingredients has been proposed for the treatment of amyotrophic lateral sclerosis.

Ushahidi wa Apoaekuorini

There are no high-quality studies demonstrating that apoaequorin is effective for improving memory loss or for treating any health condition.

In 2017, the Federal Trade Commission (FTC) and New York State Attorney General charged the marketers of the dietary supplement Prevagen with making false and unsubstantiated claims (see FTC press release, January 9, 2017).

Athari Mbaya za Apoaekuorini

Side effects of apoaequorin may include headache, dizziness, nausea, memory problems, difficulty sleeping, and anxiety. Overall, the safety of apoaequorin is not known.

Mwingiliano wa Dawa na Apoaekuorini

The risk for serious drug interactions with apoaequorin is not known.

Mapendekezo ya Apoaekuorini

No beneficial health effects of apoaequorin, including improving memory, have been confirmed in high-quality studies in people.

Use of apoaequorin is not recommended because there are no confirmed benefits to outweigh the possibility of negative side effects.