Oral Adrenergic Agents for Hypertension in Children

Oral Adrenergic Agents for Hypertension in Children

Medication (Class)

Some Adverse Effects

Comments

Atenolol (beta-blocker)Atenolol (beta-blocker)

May cause bradycardia or atrioventricular block, or fatigue/lethargy, depressed mood, depressed appetite, dizziness, or wheezing

Contraindications include pulmonary edema and cardiogenic shock.

Use with caution in patients with diabetes and asthma. Use with caution in teenagers with pre-existing depression.

Atenolol should not be abruptly stopped. Atenolol should not be abruptly stopped.

Clonidine (alpha-2-agonist)Clonidine (alpha-2-agonist)

Drowsiness, fatigue, dizziness

Clonidine should not be abruptly stopped.Clonidine should not be abruptly stopped.

Labetalol (mixed alpha- and beta-blocker)Labetalol (mixed alpha- and beta-blocker)

Orthostatic hypotension, edema, bradycardia, heart failure, bronchospasm

Contraindications include pulmonary edema, cardiogenic shock, or heart block.

Use with caution in patients with asthma or hepatic disease.