Medications for Inflammatory Bowel Disease
Category | Mechanism | Medication |
|---|---|---|
Glucocorticoids | Regulation of gene expression | Hydrocortisone (IV)Hydrocortisone (IV) Methylprednisolone (IV)Methylprednisolone (IV) Prednisone (oral)Prednisone (oral) Prednisolone (oral)Prednisolone (oral) Budesonide (oral)Budesonide (oral) Budesonide MMX (enteric coated slow release)Budesonide MMX (enteric coated slow release) Hydrocortisone (enema or foam)Hydrocortisone (enema or foam) |
Immunomodulators (antimetabolites) | Thiopurines | AzathioprineAzathioprine 6-Mercaptopurine (6MP)6-Mercaptopurine (6MP) |
Antifolate | MethotrexateMethotrexate | |
Biologic Agents | Anti-TNF antibodies | InfliximabInfliximab AdalimumabAdalimumab Certolizumab GolimumabGolimumab |
Antibodies to leukocyte adhesion molecules | VedolizumabVedolizumab NatalizumabNatalizumab | |
Anti-IL-23 and related antibodies | MirikizumabMirikizumab RisankizumabRisankizumab Ustekinumab (anti-IL 12/23)Ustekinumab (anti-IL 12/23) Guselkumab (anti-p19 subunit of IL23))Guselkumab (anti-p19 subunit of IL23)) | |
Small Molecules | Janus kinase (JAK) inhibitors | TofacitinibTofacitinib UpadacitinibUpadacitinib |
Sphingosine 1-phosphate (S1P) receptor modulators | OzanimodOzanimod EtrasimodEtrasimod | |
Other Immunosuppressants | Calcineurin inhibitors | CyclosporineCyclosporine TacrolimusTacrolimus |