Features Distinguishing Athlete's Heart From Cardiomyopathy

Features Distinguishing Athlete's Heart From Cardiomyopathy

Feature

Athlete’s Heart

Cardiomyopathy

Left ventricular septal thickness*

In males, < 13 mm

In females, < 11 mm

In males, > 15 mm

In females, > 13 mm

Left ventricular end-diastolic diameter†

< 60 mm

> 70 mm

Diastolic function

Normal (E:A ratio > 1‡)

septal e' ≥ 10 cm/sec

lateral e' ≥ 12 cm/sec

Abnormal (E:A ratio < 1)

septal e' < 10 cm/sec

lateral e' < 12 cm/sec

Systolic function

Global longitudinal strain more negative than -16%

Global longitudinal strain less negative than -16%

Septal hypertrophy

Symmetric

Asymmetric (in hypertrophic cardiomyopathy)

Family history of cardiomyopathy or sudden cardiac death

None

May be present

Blood pressure response to exercise

Normal

Normal or reduced systolic blood pressure response

Deconditioning

Left ventricular hypertrophy regression

No left ventricular hypertrophy regression

* A value of 13 to 15 mm in males and 11 to 13 mm in females is indeterminate.

† A value of 60 to 70 mm is indeterminate.

‡ E:A ratio = ratio of early to late atrial transmitral flow velocity.

Finocchiaro G, Westaby J, Sheppard MN, Papadakis M, Sharma S. Sudden Cardiac Death in Young Athletes: JACC State-of-the-Art Review. J Am Coll Cardiol. 2024;83(2):350-370. doi:10.1016/j.jacc.2023.10.032

* A value of 13 to 15 mm in males and 11 to 13 mm in females is indeterminate.

† A value of 60 to 70 mm is indeterminate.

‡ E:A ratio = ratio of early to late atrial transmitral flow velocity.

Finocchiaro G, Westaby J, Sheppard MN, Papadakis M, Sharma S. Sudden Cardiac Death in Young Athletes: JACC State-of-the-Art Review. J Am Coll Cardiol. 2024;83(2):350-370. doi:10.1016/j.jacc.2023.10.032

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