Thrombocytopenia and Platelet Dysfunction

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• Overview of Platelet Disorders
  • Etiology
    • Thrombocythemia and thrombocytosis
    • Thrombocytopenia
    • Platelet dysfunction
    • Etiology reference
  • Symptoms and Signs
  • Diagnosis
    • Thrombocytopenia
    • Suspected platelet dysfunction
    • Diagnosis reference
  • Treatment

• Acquired Platelet Dysfunction
  • Medications
  • Systemic disorders
  • Cardiopulmonary bypass
  • References

• Inherited Platelet Function Disorders
  • Disorders of platelet adhesion
  • Disorders of platelet activation

• Immune Thrombocytopenia (ITP)
  • General references
  • Symptoms and Signs
  • Diagnosis
    • Diagnosis reference
  • Treatment
    • Second-line medical therapies
    • Life-threatening bleeding in ITP
    • Treatment of children with ITP
    • Treatment references
  • Prognosis
    • Prognosis reference
  • Key Points

• Thrombocytopenia Due to Splenic Sequestration
  • Reference

• Thrombocytopenia: Other Causes
  • Acute respiratory distress syndrome
  • Blood transfusions
  • Systemic rheumatic and lymphoproliferative disorders
  • Medication-induced platelet destruction
  • Heparin-induced thrombocytopenia
  • Infections
  • Pregnancy
  • Sepsis
  • Reference

• Hemolytic-Uremic Syndrome (HUS)
  • Pathophysiology
  • Etiology
  • Symptoms and Signs
  • Diagnosis
    • Diagnosis of cause
    • Diagnosis references
  • Treatment
    • Treatment reference
  • Key Points

• Thrombotic Thrombocytopenic Purpura (TTP)
  • Pathophysiology
  • Etiology
    • Etiology reference
  • Symptoms and Signs
  • Diagnosis
    • Diagnosis reference
  • Treatment
    • Treatment references
  • Key Points

• Von Willebrand Disease
  • Symptoms and Signs
  • Diagnosis
    • Diagnosis reference
  • Treatment
    • Treatment reference
  • Key Points