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Effects of Amyloid Buildup

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Organ or System Affected	Possible Consequences
Blood vessels	Easy bruising
Brain	Alzheimer disease, cerebral amyloid angiopathy
Digestive system	Constipation or diarrhea Enlarged tongue (macroglossia) Weight loss Poor nutrient absorption
Heart	Abnormal heart rhythms (arrhythmias) Enlarged heart Heart failure
Kidneys	Fluid accumulation in tissues, causing swelling (edema) Kidney failure
Liver	Enlarged liver
Lungs and airway	Difficulty breathing Wheezing
Lymph nodes	Enlarged lymph nodes
Musculoskeletal system	Carpal tunnel syndrome , spinal stenosis, tendon rupture
Nerves	Numbness Tingling Light-headedness
Skin	Bruises Nodules
Thyroid gland	Enlarged thyroid gland