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Rotavirus Vaccine

By

Margot L. Savoy

, MD, MPH, Lewis Katz School of Medicine at Temple University

Last full review/revision Jun 2021| Content last modified Jun 2021
Click here for the Professional Version

The rotavirus vaccine is a live-virus vaccine that helps protect against gastroenteritis Rotavirus Infection Rotavirus is a common and very contagious virus that causes vomiting and diarrhea. Rotavirus is a viral infection of the digestive tract that can cause severe dehydration. Typical symptoms include... read more Rotavirus Infection caused by rotavirus, which causes vomiting, diarrhea, and, if symptoms persist, dehydration and organ damage.

Two formulations of rotavirus virus are available. Both contain live but weakened (attenuated) rotavirus.

For more information, see the Centers for Disease Control and Prevention's (CDC) Rotavirus vaccine information statement.

Administration of Rotavirus Vaccine

The rotavirus vaccine is part of the recommended vaccination schedule for children Childhood Vaccination Schedule Most doctors follow the vaccination schedule recommended by the Centers for Disease Control and Prevention (CDC—see the schedule for infants and children and the schedule for older children... read more . This vaccine is given by mouth. Two or three doses are given, depending on the formulation: at age 2 months and 4 months or at 2 months, 4 months, and 6 months.

People who have had serious allergic reactions to a previous dose of the vaccine or to a vaccine component should not be given the rotavirus vaccine.

If people have a temporary illness, doctors usually wait to give the vaccine until the illness resolves.

Side Effects of Rotavirus Vaccine

Infants may have mild, temporary diarrhea or vomiting. They may become irritable.

When an older rotavirus vaccine was used, the risk of intussusception was increased. In intussusception, the intestine is blocked because one segment of the intestine slides into another, much like the parts of a telescope. The older vaccine was taken off the market in the United States. The newer vaccines, when given as recommended, may increase the risk of intussusception but only slightly.

More Information

The following are some English-language resources that may be useful. Please note that THE MANUAL is not responsible for the content of these resources.

NOTE: This is the Consumer Version. DOCTORS: Click here for the Professional Version
Click here for the Professional Version
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Test your knowledge

Human Immunodeficiency Virus (HIV) Infection
Human immunodeficiency virus (HIV) infection is a viral infection that progressively destroys certain white blood cells. Untreated, it usually leads to acquired immunodeficiency syndrome (AIDS). Transmission of HIV requires contact with bodily fluid that contains the virus or cells infected with the virus. Which of the following is not a bodily fluid that commonly transmits HIV? 
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