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Ependymomas

By

Renee Gresh

, DO, Nemours A.I. duPont Hospital for Children

Last full review/revision Jun 2021| Content last modified Jun 2021
Click here for the Professional Version
Topic Resources

Ependymomas are slow-growing brain tumors that develop from cells lining the spaces within the brain (ventricles).

  • The cause of ependymomas is not known.

  • Some symptoms are vomiting, listlessness, and problems with balance.

  • Diagnosis is made by an imaging test and a biopsy.

  • The prognosis depends on the child's age and on how much of the cancer is removed.

  • Treatment includes surgery, chemotherapy, and radiation therapy.

Ependymomas are the third most common brain tumor in children Overview of Brain Tumors in Children Brain tumors (also see brain tumors in adults) are the second most common cancer in children younger than 15 years of age (after leukemia) and the second leading cause of death from cancer.... read more , accounting for 10%. The majority of children diagnosed with ependymoma are younger than 8 years of age. About one third of cases occur in children younger than 3 years of age.

Most ependymomas develop in or near the back of the brain at the bottom of the skull (called the posterior fossa). This area contains the cerebellum (which helps control coordination and balance) and the brain stem (which controls critical body functions such as breathing). Ependymomas tend to spread to the brain stem. Sometimes ependymomas develop in the spinal cord.

Symptoms of Ependymomas

The first symptoms of ependymoma often result from increased pressure within the skull. They include headaches, vomiting, and listlessness. Infants may not meet developmental milestones. They may be irritable and have no appetite. Mood or personality may change, and children may have difficulty concentrating. Children have problems with balance, coordination, and walking. Some children have seizures.

Ependymomas in the spinal cord may cause back pain, and children may have difficulty controlling urination and bowel movements.

Diagnosis of Ependymomas

  • Magnetic resonance imaging (MRI) and biopsy

Prognosis for Ependymomas

How well children do depends on the child's age and on how much of the tumor can be removed.

Children who survive are at risk of developing problems with their brain, spinal cord, and nerves.

Treatment of Ependymomas

More Information

The following is an English-language resource that may be useful. Please note that THE MANUAL is not responsible for the content of this resource.

  • American Cancer Society: If Your Child Is Diagnosed With Cancer: A resource for parents and loved ones of a child who has cancer that provides information about how to cope with some of the problems and questions that come up just after a child is diagnosed

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