Пероральні блокатори кальцієвих каналів для лікування гіпертензії

Dihydropyridines

Amlodipine

Dizziness, flushing, headache, weakness, nausea, heartburn, peripheral edema, tachycardia

Possible gingival hyperplasia with chronic use

Contraindicated in heart failure, possibly except for amlodipine

Use of short-acting nifedipine possibly associated with higher rate of myocardial infarction

Felodipine

Isradipine

Nicardipine

Nicardipine, sustained-release

Nifedipine, extended-release

Nisoldipine

Nondihydropyridines

Diltiazem, sustained-release

Headache, dizziness, asthenia, flushing, peripheral edema, bradycardia; possibly liver dysfunction

Possible gingival hyperplasia with chronic use

Verapamil: Constipation

Contraindicated in heart failure with reduced ejection fraction due to negative inotropic effects, in sinus node dysfunction, or in greater than first-degree atrioventricular block

Diltiazem, extended-release

Verapamil

Verapamil, sustained-release