Пероральні блокатори кальцієвих каналів (БКК) для лікування гіпертензії у дітей

Amlodipine

For children 1–5 years of age: Initial dose 0.1 mg/kg once a day, up to a maximum dose 0.6 mg/kg (not to exceed 5 mg) once a day

For children ≥ 6 years of age: Initial dose 2.5 mg once a day, up to a maximum dose 10 mg once a day

Common adverse effects: Flushing, dizziness, peripheral edema

Severe adverse effects: Angioedema

Contraindications include hypersensitivity to CCBs.

Isradipine

Extended-release tablet: Initial dose 2.5 mg once a day, up to maximum dose 10 mg once a day

Nifedipine, extended-release†

Initial dose: 0.25–0.5 mg/kg once a day up to maximum dose 3 mg/kg (not to exceed 120 mg) once a day (or 1.5 mg/kg or 60 mg twice a day)