Інотропні та вазоактивні катехоламіни
Medication | Dosage | Hemodynamic Actions |
|---|---|---|
Dobutamine | 2.5–10 mcg/kg/minute | Beta-adrenergic: Inotropic effects* |
Dopamine | 2–10 mcg/kg/minute for low dose 20 mcg/kg/minute for high dose | Alpha-adrenergic: Vasoconstriction† Beta-adrenergic: Inotropic and chronotropic effects and vasodilation† Nonadrenergic: Renal and splanchnic vasodilation |
Norepinephrine | 2–12 mcg/minute OR 0.1 mcg/kg/minute (weight-based dosing) | Alpha-adrenergic: Vasoconstriction Beta-adrenergic: Inotropic and chronotropic effects |
* Chronotropic, arrhythmogenic, and direct vascular effects are minimal at lower doses. | ||
† Effects depend on dosage and underlying pathophysiology. | ||
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