MSD Manual

Please confirm that you are a health care professional

Loading

Peripheral Neuropathy

By

Michael Rubin

, MDCM,

  • Weill Cornell Medical College
  • New York Presbyterian Hospital-Cornell Medical Center

Last full review/revision Dec 2020| Content last modified Dec 2020
Click here for Patient Education

Peripheral neuropathy is dysfunction of one or more peripheral nerves (the part of a nerve distal to the root and plexus). It includes numerous syndromes characterized by varying degrees of sensory disturbances, pain, muscle weakness and atrophy, diminished deep tendon reflexes, and vasomotor symptoms, alone or in any combination. Initial classification is based on history and physical examination. Electromyography and nerve conduction studies (electrodiagnostic testing) help localize the lesion and determine whether the pathophysiology is primarily axonal (often metabolic) or demyelinating (often autoimmune). Treatment is aimed mainly at the cause.

Peripheral neuropathy may affect

Click here for Patient Education
NOTE: This is the Professional Version. CONSUMERS: Click here for the Consumer Version
Professionals also read

Also of Interest

SOCIAL MEDIA

iOS Android
iOS Android
iOS Android
TOP