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Some Targeted Therapy Drugs for Non–Small Cell Lung Cancer

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Target	Drug	NSCLC
ALK rearrangement	AlectinibAlectinib BrigatinibBrigatinib CeritinibCeritinib CrizotinibCrizotinib	Adenocarcinoma
BRAF mutation	DabrafenibDabrafenib Trametinib Trametinib	Adenocarcinoma Squamous cell carcinoma
EGFR mutation	AfatinibAfatinib ErlotinibErlotinib GefitinibGefitinib Necitumumab Necitumumab	Adenocarcinoma Squamous cell carcinoma
EGFR (T790M mutation)	Osimertinib Osimertinib	Adenocarcinoma
Inhibit blood vessel growth	BevacizumabBevacizumab Ramucirumab Ramucirumab	Adenocarcinoma
Immune activation (checkpoint inhibitors)	AtezolizumabAtezolizumab CemiplimabCemiplimab DurvalumabDurvalumab IpilimumabIpilimumab NivolumabNivolumab PembrolizumabPembrolizumab	Adenocarcinoma Squamous cell carcinoma
NSCLC = Non–small cell lung cancer.