A

Streptococcus pyogenes

Beta

Pharyngitis, tonsillitis, wound and skin infections, septicemia, scarlet fever, pneumonia, rheumatic fever, glomerulonephritis, endocarditis (rare)

Penicillin

Necrotizing fasciitis

Expeditious surgical management

B

S. agalactiae

Beta

Sepsis, postpartum or neonatal sepsis, meningitis, skin infections, endocarditis, septic arthritis, urinary tract infection

C and G

S. equi, S. equimilis, S. zooepidemicus, S. canis

Beta

Pharyngitis, pneumonia, cellulitis, pyoderma, erysipelas, impetigo, wound infections, puerperal sepsis, neonatal sepsis, endocarditis, septic arthritis

Human infection with group C implies a zoonotic origin

D

Enterococcal:† Enterococcus faecalis, E. faecium

Nonenterococcal: S. gallolyticus (formerly S. bovis), S. equinus

Alpha or gamma

Endocarditis, urinary tract infection, intra-abdominal infection, cellulitis, wound infection as well as concurrent bacteremia

S. gallolyticus (formerly S. bovis biotype I)

Colonic adenomas or carcinomas, endocarditis

Viridans‡

S. mutans, S. sanguis, S. salivarius, S. mitis (formerly S. mitior), S. anginosus (formerly S milleri), S. constellatus, S. intermedius

Alpha or gamma

Endocarditis, bacteremia, meningitis, localized infection, abscesses (particularly S. anginosus)

S. suis

Meningitis, sometimes toxic shock syndrome

S. iniae

Cellulitis, invasive infections from fish

Penicillin