Proteeae Infections

ByLarry M. Bush, MD, FACP, Charles E. Schmidt College of Medicine, Florida Atlantic University;
Maria T. Vazquez-Pertejo, MD, FACP, Wellington Regional Medical Center
Reviewed/Revised Apr 2022
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    The Proteeae are normal fecal flora that often cause infection in patients whose normal flora have been disturbed by antibiotic therapy.

    The Proteeae constitute at least 3 genera of gram-negative organisms:

    • Proteus: P. mirabilis, P. vulgaris, and P. myxofaciens

    • Morganella: M. morganii

    • Providencia: P. rettgeri, P. alcalifaciens, and P. stuartii

    However, P. mirabilis causes most human infections. These organisms are normal fecal flora and are present in soil and water. They are often present in superficial wounds, draining ears, and sputum, particularly in patients whose normal flora has been eradicated by antibiotic therapy. They may cause bacteremia and deep-seated infections, particularly in the ears and mastoid sinuses, peritoneal cavity, and urinary tract of patients with chronic urinary tract infections or with renal or bladder stones; Proteus

    P. mirabilisP. mirabilis is an emerging problem.

    Indole-positive species (P. vulgaris, M. morganii, P. rettgeri

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