What are nerves?
A nerve is a bundle of nerve fibers from many nerve cells The Nerves A nerve is a bundle of nerve fibers from many nerve cells. The fibers are bundled together for strength and protection from injury. Your nerves are like signal wires Nerves send messages back... read more . The fibers are bundled together for strength and protection from injury.
Your nerves are like signal wires
Nerves send messages back and forth between your brain or spinal cord and your body
The messages from the brain tell your body what to do
Messages from the body let your brain know what is happening in your body
When nerves to part of your body are injured or don't work you may not be able to move or feel that part of your body
How do nerves work?
There are billions and billions of nerve cells in your brain, your spinal cord, and in groups just outside your spinal cord.
Each nerve cell has a microscopic body:
The body of the nerve cell is responsible for processing nutrients and keeping the cell alive
Each nerve cell body has fibers going to and from it:
Input fibers receive signals from other nerve cells or from receptors in your sense organs
Output fibers send signals to other nerves, to muscles, or to other organs
Signals travel only one way in a nerve cell
Sometimes nerve fibers are dozens of centimeters long. For example, a single nerve fiber may run from near your spinal cord all the way to your toe. Some nerve fibers that go to your skin or your organs have sensory receptors. For example, the receptors at the end of nerve fibers in your skin detect things that are sharp or hot.
Because each individual nerve fiber is very tiny, the fibers are bundled together for strength. Large fibers leave your spinal cord The Spinal Cord The spinal cord is a long tube made up of nerves that goes from the brain down your back through the hollow center of your spine. The spinal cord is like a thick electrical cable that carries... read more and split like the branches of a tree to go all the different parts of your body. Different nerves carry signals to and from a specific part of your body.
Although nerve fibers and their signals act a lot like a wire carrying electrical signals, that's not exactly right. Nerve cells really send their signals using chemicals.
Chemical changes take place progressively along the length of a nerve fiber
Those changes are quick but not nearly as fast as electricity
When the chemical changes reach the end of the nerve fiber, they release other chemicals called neurotransmitters
The neurotransmitters drift across a microscopic gap where they hit the chemical receptors of another cell
The neurotransmitters trigger chemical changes in that other cell
If that cell is a nerve cell, then the progressive chemical changes continue down the fibers of that cell to pass the signal along
To help the chemical signals travel quickly, nerve fibers are wrapped in a fatty layer called a myelin sheath. If the myelin sheath is damaged, messages either aren't passed or are passed more slowly along nerves.
Insulating a Nerve Fiber
Most nerve fibers inside and outside the brain are wrapped with many layers of tissue composed of a fat (lipoprotein) called myelin. These layers form the myelin sheath. Much like the insulation around an electrical wire, the myelin sheath enables nerve signals (electrical impulses) to be conducted along the nerve fiber with speed and accuracy. When the myelin sheath is damaged (called demyelination), nerves do not conduct electrical impulses normally.
What can go wrong with nerves?
Many problems can affect the nerves:
Injuries can cut or damage nerves
Pressure on a nerve, such as from carpal tunnel syndrome Carpal Tunnel Syndrome Carpal tunnel syndrome is pain, numbness, and tingling in your fingers and hand. Those feelings are caused by pressure on a nerve in your wrist. The carpal tunnel is a space (channel) on the... read more , can keep the nerve from working properly
Diseases that damage the myelin sheath, such as multiple sclerosis Multiple Sclerosis (MS) In multiple sclerosis, patches of myelin (the substance that covers most nerve fibers) and underlying nerve fibers in the brain, optic nerves, and spinal cord are damaged or destroyed. The cause... read more , keep messages from being passed properly
Diseases such as diabetes Diabetes Diabetes is a disease in which your blood sugar (glucose) levels are too high. You get diabetes if your body's normal way of controlling blood sugar isn't working right. There are 2 types of... read more and poor circulation can damage nerve fibers
Nerve fibers can become inflamed by autoimmune disorders Autoimmune Diseases "Auto" is a medical term for "self." The immune system is your body's defense system. It helps protect you from illness and infection. The immune system usually attacks invading bacteria, viruses... read more , such as Guillain-Barré syndrome Guillain-Barré Syndrome (GBS) Guillain-Barré syndrome (GBS) is muscle weakness that happens over a few days or a few weeks. GBS is probably caused by an autoimmune reaction (when your body's immune system attacks parts of... read more
Certain medicines and poisons damage nerve fibers
Once nerve cells die, they can't grow back. However, if the body of the nerve cell isn't hurt, nerve fibers sometimes grow back slowly. Doctors sometimes can sew cut nerves back together and get them to work. Damage to the myelin sheath is usually permanent.