Psychological Factors Affecting Other Medical Conditions

ByJoel E. Dimsdale, MD, University of California, San Diego
Reviewed/Revised Aug 2022
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    Psychological factors affecting other medical conditions is diagnosed when psychologic or behavioral factors adversely affect the course or outcome of an existing medical condition.

    (See also Overview of Somatization.)

    Patients have one or more clinically significant psychologic or behavioral factors that adversely affect an existing medical disorder (eg, diabetes mellitus, heart disease) or symptom (eg, pain). These factors may increase the risk of suffering, death, or disability; aggravate an underlying medical condition; or result in hospitalization or emergency department visit. Abnormal psychologic or behavioral responses to a medical condition that do not affect medical outcome are considered an adjustment disorder.

    Psychologic or behavioral factors that can adversely affect a medical disorder include

    • Denial of the significance or severity of symptoms

    • Poor adherence to prescribed testing and treatment

    Patients may present as treatment failures or with aggravation of medical conditions associated with stress (eg, Takotsubo cardiomyopathy).

    Patient education and psychotherapeutic intervention can help.

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