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Introduction to Concepts in Pharmacotherapy

By

Shalini S. Lynch

, PharmD, University of California San Francisco School of Pharmacy

Last full review/revision May 2022| Content last modified Sep 2022
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Drugs are selected based on characteristics of the drug (eg, efficacy Drug Efficacy and Safety Obviously, a drug (or any medical treatment) should be used only when it will benefit a patient. Benefit takes into account both the drug's ability to produce the desired result (efficacy) and... read more , safety profile Drug Efficacy and Safety Obviously, a drug (or any medical treatment) should be used only when it will benefit a patient. Benefit takes into account both the drug's ability to produce the desired result (efficacy) and... read more , route of administration Drug Absorption Drug absorption is determined by the drug’s physicochemical properties, formulation, and route of administration. Dosage forms (eg, tablets, capsules, solutions), consisting of the drug plus... read more , route of elimination Drug Excretion The kidneys are the principal organs for excreting water-soluble substances. The biliary system contributes to excretion to the degree that drug is not reabsorbed from the gastrointestinal ... read more , dosing frequency, cost Economic Analyses in Clinical Decision Making Given limited societal and personal resources and restrictions under health insurance, cost considerations have become more relevant in clinical decision making. Limited resources should not... read more ) and of the patient (eg, age, sex, other medical problems, likelihood of pregnancy, ethnicity, and other genetic determinants). Other drugs that the patient may be taking can also influence the physician's drug selection. Risks and benefits of the drug are also assessed; every drug poses some risk.

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NOTE: This is the Professional Version. CONSUMERS: Click here for the Consumer Version
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