(See also Overview of Gastrointestinal Emergencies.)
Ischemic colitis results from an interruption of blood flow through arteries that supply the large intestine. Often doctors cannot find a cause for the reduced blood flow, but it is more common among people with heart and blood vessel disease, people who have had surgery on their aorta, or people who have problems with increased blood clotting. Ischemic colitis primarily affects people who are 60 or older.
Reduction of blood flow damages the inside lining and inner layers of the wall of the large intestine, causing ulcers (sores) in the lining of the large intestine, which can bleed.
Usually, the person has abdominal pain. The pain is felt more often on the left side, but it can occur anywhere in the abdomen. The person frequently passes loose stools that are often accompanied by dark red clots. Sometimes bright red blood is passed without stool. Low fevers (usually below 100° F [37.7° C]) are common.
A doctor may suspect ischemic colitis on the basis of the symptoms of pain and bleeding, especially in a person older than 60. It is important for doctors to distinguish ischemic colitis from acute mesenteric ischemia, a more dangerous condition in which blood flow to part of the intestine is completely and irreversibly blocked.
Nearly all people with ischemic colitis improve and recover over a period of 1 to 2 weeks. However, when the interruption to the blood supply is more severe or more prolonged, the affected portion of the large intestine may have to be surgically removed. Rarely, people get better but later on develop scar tissue in the affected area.
People with ischemic colitis are hospitalized. Initially, the person is given neither fluids nor food by mouth so that the intestine can rest. Fluids, electrolytes, antibiotics, and nutrients are given by vein (intravenously). Within a few days, eating is resumed.
If people develop scar tissue, surgical repair may be needed.