MSD Manual

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Introduction to Symptoms of Musculoskeletal Disorders

By

Alexandra Villa-Forte

, MD, MPH, Cleveland Clinic

Reviewed/Revised Feb 2023
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Common symptoms of musculoskeletal disorders include

Inflammation may cause pain, swelling, warmth, tenderness, impaired function, and sometimes redness of the overlying skin. Inflammation can result from many different musculoskeletal disorders, such as autoimmune disorders (for example, rheumatoid arthritis Rheumatoid Arthritis (RA) Rheumatoid arthritis is an inflammatory arthritis in which joints, usually including those of the hands and feet, are inflamed, resulting in swelling, pain, and often destruction of joints.... read more Rheumatoid Arthritis (RA) ) and infections. When inflammation affects a joint, fluid may accumulate inside the joint, causing pain, swelling, and decreased range of motion.

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