Important: The authors, reviewers, and editors of this material have made extensive efforts to ensure that treatments, drugs, and dosage regimens are accurate and conform to the standards accepted at the time of publication. However, constant changes in information resulting from continuing research and clinical experience, reasonable differences in opinions among authorities, unique aspects of individual clinical situations, and the possibility of human error in preparing such an extensive text require that the reader exercise individual judgment when making a clinical decision and, if necessary, consult and compare information from other sources. In particular, the reader is advised to check the drug’s product insert before prescribing or administering it, especially if the drug is unfamiliar or is used infrequently.
Content in the Manuals reflects medical practice and information in the United States. Outside of the United States, clinical guidelines, practice standards, and professional opinion may differ and the reader is advised to also consult local medical sources. Please note, not all content that is available in English is available in every language.