默沙东 诊疗手册

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What Is the Risk of Having a Baby With a Chromosomal Abnormality*?

What Is the Risk of Having a Baby With a Chromosomal Abnormality*?

孕妇年龄

染色体异常风险

20

0.2%

35

0.5%

40

1.5%

49

14%

* 此表仅包括可由标准染色体测试来检测的染色体异常。不包括婴儿亚显微染色体异常(仅可以通过特殊测试检测)的风险。

数据信息源自 Hook EB:不同年龄产妇染色体异常率。Obstetrics and Gynecology 58:282-285, 1981; Hook EB, Cross PK, Schreinemachers DM: 活产婴儿羊膜穿刺术染色体异常率。Journal of the American Medical Association 249 (15):2034-2038, 1983; and Savva GM, Walker K, Morris JK. 与 21 三体综合征(唐氏综合征)相比,13 三体综合征和 18 三体综合征的特定年龄产妇的活产盛行率。Prenatal Diagnosis 30:57–64, 2010.