Glomerular Filtration Rate Estimate by CKD-EPI Equation

 
Input:
 
Sex    Female      Male    
 
Race White or Other (1)

Black (1.159)
Age  
Serum creatinine  

 
Result:
 
GFR   mL/min/1.73m2
 
Decimal Precision  
 
Notes
  • Equation parameters such as Race, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (1), represent the values that will be used.
  • GFR is estimated by an equation developed by the Chronic Kidney Disease Epidemiology Collaboration.
  • GFR = 141 * min(Serum_creatinine/kappa, 1)alpha * max(Serum_creatinine/kappa, 1) -1.209 * 0.993Age * Sex * Race
  • For females, the following values are used: Sex = 1.018; alpha = -0.329; kappa = 0.7
  • For males, the following values are used: Sex = 1; alpha = -0.411; kappa = 0.9

 
References
  1. Levey AS, Stevens LA, Schmid CH, et al. for the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). A New Equation to Estimate Glomerular Filtration Rate. Ann Intern Med. 2009 May 5;150(9):604-612. PubMed ID: 19414839 PubMed Logo
  2. Hsu CY. ACP Journal Club. CKD-EPI eGFR categories were better than MDRD categories for predicting mortality in a range of populations. Ann Intern Med. 2012 Nov 20;157(10):JC5-12. doi: 10.7326/0003-4819-157-10-201211200-02012. PubMed ID: 23165688 PubMed Logo
  3. Matsushita K, Mahmoodi BK, Woodward M, et al., Chronic Kidney Disease Prognosis Consortium. Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA. 2012 May 9;307(18):1941-51. doi: 10.1001/jama.2012.3954. PubMed ID: 22570462 PubMed Logo
  4. Parsh J, Seth M, Aronow H, et al. Choice of Estimated Glomerular Filtration Rate Equation Impacts Drug-Dosing Recommendations and Risk Stratification in Patients With Chronic Kidney Disease Undergoing Percutaneous Coronary Interventions. J Am Coll Cardiol. 2015 Jun 30;65(25):2714-23. PubMed ID: 26112195 PubMed Logo

 

 
 
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