Table: Drugs for Serious Fungal Infections - MSD Manual Consumer Version

Drugs for Serious Fungal Infections

Drug	Common Uses	Some Side Effects
Amphotericin B	Most fungal infections	Chills, fever, headache, vomiting, a low potassium level* in the blood, kidney failure, and anemia
Anidulafungin Caspofungin Micafungin	Aspergillus Aspergillosis Aspergillosis is an infection, usually of the lungs, caused by the fungus Aspergillus. A ball of fungus fibers, blood clots, and white blood cells may form in the lungs or sinuses. People... read more and candidal infections Candidiasis Candidiasis is a fungal infection caused by several species of the yeast Candida, especially Candida albicans. The most common type of candidiasis is a superficial infection of... read more	Nausea, diarrhea, headache, liver inflammation, inflammation of the veins, and rash
Fluconazole	Candidal Candidiasis Candidiasis is a fungal infection caused by several species of the yeast Candida, especially Candida albicans. The most common type of candidiasis is a superficial infection of... read more and other fungal infections, including coccidioidomycosis Coccidioidomycosis Coccidioidomycosis is an infection, usually of the lungs, caused by the fungus Coccidioides immitis or Coccidioides posadasii. The infection is caused by inhaling spores of the... read more and cryptococcal Cryptococcosis Cryptococcosis is an infection caused by the fungus Cryptococcus neoformans or Cryptococcus gattii. People may have no symptoms or may have headache and confusion, a cough and... read more infections	Nausea, rash, and liver inflammation
Flucytosine†	Candidal Candidiasis Candidiasis is a fungal infection caused by several species of the yeast Candida, especially Candida albicans. The most common type of candidiasis is a superficial infection of... read more and cryptococcal Cryptococcosis Cryptococcosis is an infection caused by the fungus Cryptococcus neoformans or Cryptococcus gattii. People may have no symptoms or may have headache and confusion, a cough and... read more infections	Nausea, vomiting, and bone marrow damage
Isavuconazole	Aspergillosis Aspergillosis Aspergillosis is an infection, usually of the lungs, caused by the fungus Aspergillus. A ball of fungus fibers, blood clots, and white blood cells may form in the lungs or sinuses. People... read more and mucormycosis Mucormycosis Mucormycosis is a fungal infection that can be caused by many different molds. Mucormycosis is acquired when spores produced by the mold are inhaled or, much less commonly, when they enter the... read more	Nausea, vomiting, and liver inflammation
Itraconazole	Fungal skin infections, histoplasmosis Histoplasmosis Histoplasmosis is an infection caused by the fungus Histoplasma capsulatum. It occurs mainly in the lungs but can sometimes spread throughout the body. Histoplasmosis is acquired by inhaling... read more , blastomycosis Blastomycosis Blastomycosis is an infection, mainly of the lungs, caused by the fungus Blastomyces dermatitidis. People have a fever, chills, and drenching sweats and sometimes chest pain, difficulty... read more , coccidioidomycosis Coccidioidomycosis Coccidioidomycosis is an infection, usually of the lungs, caused by the fungus Coccidioides immitis or Coccidioides posadasii. The infection is caused by inhaling spores of the... read more , and sporotrichosis Sporotrichosis Sporotrichosis is an infection caused by the fungus Sporothrix schenckii. The infection develops when the fungi enter the body through small cuts and scrapes in the skin. Usually, the... read more	Nausea, diarrhea, liver inflammation, rash, headache, dizziness, a low potassium level* in the blood, high blood pressure, accumulation of fluid (edema), and heart failure
SUBA-itraconazole	Histoplasmosis Histoplasmosis Histoplasmosis is an infection caused by the fungus Histoplasma capsulatum. It occurs mainly in the lungs but can sometimes spread throughout the body. Histoplasmosis is acquired by inhaling... read more , blastomycosis Blastomycosis Blastomycosis is an infection, mainly of the lungs, caused by the fungus Blastomyces dermatitidis. People have a fever, chills, and drenching sweats and sometimes chest pain, difficulty... read more , and aspergillosis Aspergillosis Aspergillosis is an infection, usually of the lungs, caused by the fungus Aspergillus. A ball of fungus fibers, blood clots, and white blood cells may form in the lungs or sinuses. People... read more	Nausea, diarrhea, liver inflammation, rash, headache, dizziness, a low potassium level* in the blood, high blood pressure, accumulation of fluid (edema), and heart failure
Posaconazole	Aspergillus Aspergillosis Aspergillosis is an infection, usually of the lungs, caused by the fungus Aspergillus. A ball of fungus fibers, blood clots, and white blood cells may form in the lungs or sinuses. People... read more , candidal Candidiasis Candidiasis is a fungal infection caused by several species of the yeast Candida, especially Candida albicans. The most common type of candidiasis is a superficial infection of... read more , and many other fungal infections	Nausea, vomiting, rash, and liver inflammation
Voriconazole	Aspergillus Aspergillosis Aspergillosis is an infection, usually of the lungs, caused by the fungus Aspergillus. A ball of fungus fibers, blood clots, and white blood cells may form in the lungs or sinuses. People... read more and candidal Candidiasis Candidiasis is a fungal infection caused by several species of the yeast Candida, especially Candida albicans. The most common type of candidiasis is a superficial infection of... read more infections, fusariosis, and scedosporiosis	Temporary disturbances in vision (such as blurred vision, changes in color vision, and sensitivity to light), nausea, vomiting, rash, and liver inflammation
* A low potassium level (hypokalemia) can cause muscle weakness, cramping, and twitches and abnormal heart rhythms.
† Flucytosine is usually used with amphotericin B for serious Candida and cryptococcal infections.