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Drug
Common Uses
Some Potential Side Effects
Mafenide
Sulfacetamide
Sulfadiazine
Sulfadoxine
Sulfamethizole
Sulfanilamide
Sulfasalazine
Sulfisoxazole
Trimethoprim/sulfamethoxazole Trimethoprim and Sulfamethoxazole Trimethoprim is an antibiotic and is available as a single drug or in combination with sulfamethoxazole (a sulfonamide antibiotic). Trimethoprim and the combination of trimethoprim and sulfamethoxazole... read more
Urinary tract infections Overview of Urinary Tract Infections (UTIs) In healthy people, urine in the bladder is sterile—no bacteria or other infectious organisms are present. The tube that carries urine from the bladder out of the body (urethra) contains no bacteria... read more (except sulfasalazine, sulfacetamide, and mafenide)
For sulfanilamide: Inflammation of the vagina ( vaginitis Vaginal Discharge A discharge from the vagina may occur normally or may result from inflammation of the vagina (vaginitis), often due to an infection. The genital area (vulva)—the area around the opening of the... read more )
For sulfasalazine: Inflammatory bowel disease Overview of Inflammatory Bowel Disease (IBD) In inflammatory bowel diseases, the intestine (bowel) becomes inflamed, often causing recurring abdominal pain and diarrhea. The 2 primary types of inflammatory bowel disease (IBD) are Crohn... read more
For sulfacetamide: Superficial eye infections
For mafenide and sulfadiazine: Only topically for burns
For trimethoprim/sulfamethoxazole: Skin infections caused by susceptible bacteria that are resistant to other antibiotics, including methicillin-resistant Staphylococcus aureus ( MRSA Methicillin-resistant Staphylococcus aureus (MRSA) Staphylococcus aureus is the most dangerous of all of the many common staphylococcal bacteria. These gram-positive, sphere-shaped (coccal) bacteria (see figure ) often cause skin infections... read more )
Nausea, vomiting, and diarrhea
Allergic reactions Allergies to Drugs People sometimes mistake many adverse drug reactions for allergies. For example, people who experience stomach discomfort after taking aspirin (a common adverse reaction) often say they are... read more including rashes, anaphylaxis, and angioedema
Crystals in urine (rare)
A decrease in white blood cell and platelet counts
Sensitivity to sunlight
Possibly increased tendency to bleed if used with warfarin
In people with G6PD deficiency (see table More About Some Causes of Anemia More About Some Causes of Anemia ), the breakdown of red blood cells
G6PD = deficiency of glucose-6-phosphate dehydrogenase.