MSD Manual

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Daptomycin

Daptomycin

Common Uses

Some Side Effects

Comments

Complicated skin infections, bloodstream infections, and certain heart valve infections (endocarditis) due to susceptible bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci

Gastrointestinal upset

Muscle pain and weakness

Not used when infection involves the lungs because it is made inactivate by surfactant (a substance normally produced in the lungs)