The main function of the lungs is to absorb oxygen into the bloodstream from the atmosphere and to expel carbon dioxide from the blood into the exhaled breath (gas exchange—see figure Gas Exchange Between Alveolar Spaces and Capillaries Gas Exchange Between Alveolar Spaces and Capillaries The primary function of the respiratory system is to take in oxygen and eliminate carbon dioxide. Inhaled oxygen enters the lungs and reaches the alveoli. The layers of cells lining the alveoli... read more ). For gas exchange to occur, the small air sacs within the lungs (alveoli) must remain open and filled with air. Alveoli are kept open by the elastic structure of the lung and by a liquid lining called surfactant. Surfactant counters the natural tendency of the alveoli to close (collapse). Periodic deep breaths, which people take unconsciously, and coughing also help keep alveoli open. Coughing expels any mucus or other secretions that could block the airways leading to the alveoli.
If the alveoli are closed for any reason, they cannot participate in gas exchange. The more alveoli that are closed, the less gas exchange occurs. Accordingly, atelectasis can decrease the level of oxygen in the blood. The body compensates for a small amount of atelectasis by closing off (constricting) the blood vessels in the affected area. This constriction redirects blood flow to alveoli that are open so that gas exchange can continue.
Common causes of atelectasis usually involve one of the following
The blockage may be caused by something inside the bronchus, such as a plug of mucus, a tumor, or an inhaled foreign object (such as a pill, a piece of food, or a toy). Alternatively, the bronchus may be blocked by something pressing from the outside, such as a tumor or an enlarged lymph node. Blockage from the outside can also occur if the pleural space (the space outside of the lung but inside of the chest) contains a large amount of fluid (pleural effusion Pleural Effusion Pleural effusion is the abnormal accumulation of fluid in the pleural space (the area between the two layers of the thin membrane that covers the lungs). Fluid can accumulate in the pleural... read more ) or air (pneumothorax Pneumothorax A pneumothorax is the presence of air between the two layers of pleura (thin, transparent, two-layered membrane that covers the lungs and also lines the inside of the chest wall), resulting... read more ).
When a bronchus or a smaller airway (bronchiole) becomes blocked, the air in the alveoli beyond the blockage is absorbed into the bloodstream, causing the alveoli to shrink and collapse. The area of collapsed lung may become infected because bacteria and white blood cells can build up behind (to the inside of) the blockage. Infection is particularly likely if atelectasis persists for several days or more. If atelectasis persists for months, the lung may not easily re-expand.
Any condition that decreases deep breathing or suppresses a person’s ability to cough can cause or contribute to atelectasis. Large doses of opioids or sedatives can decrease deep breathing. Atelectasis is common after general anesthesia, which temporarily suppresses a person’s cough and drive to breathe. Atelectasis is particularly common after chest or abdominal surgery because the effects of receiving general anesthesia may be added to the pain of deep breathing, so people take only shallow breaths. Chest or abdominal pain due to other causes (for example, injury or pneumonia Overview of Pneumonia Pneumonia is an infection of the small air sacs of the lungs (alveoli) and the tissues around them. Pneumonia is one of the most common causes of death worldwide. Often, pneumonia is the final... read more ) also makes taking a deep breath painful.
Certain neurologic conditions, immobility, and chest deformities can limit chest movement and thus decrease deep breathing, as can abdominal swelling. People who are very overweight or obese are also at greater risk of developing atelectasis.
Atelectasis itself does not cause any symptoms except sometimes shortness of breath. The presence and severity of shortness of breath depend on how rapidly atelectasis develops and how much of the lung is affected. If atelectasis involves a limited portion of the lung or develops slowly, symptoms may be mild or not even noticed. If a large number of alveoli are affected, particularly if atelectasis occurs rapidly, shortness of breath may be severe.
The heart rate and breathing rate may increase, and sometimes the person may look bluish (a condition called cyanosis Cyanosis Cyanosis is a bluish discoloration of the skin resulting from an inadequate amount of oxygen in the blood. Cyanosis occurs when oxygen-depleted (deoxygenated) blood, which is bluish rather than... read more ) because oxygen levels in the blood are low.
Symptoms may also reflect the disorder that caused atelectasis (for example, chest pain due to an injury) or a disorder that results from atelectasis (for example, chest pain with deep breathing, due to pneumonia Overview of Pneumonia Pneumonia is an infection of the small air sacs of the lungs (alveoli) and the tissues around them. Pneumonia is one of the most common causes of death worldwide. Often, pneumonia is the final... read more ).
Doctors suspect atelectasis based on a person’s symptoms, the physical examination findings, and the setting in which the symptoms occurred. A chest x-ray that shows the airless area confirms the diagnosis. Sometimes computed tomography (CT), bronchoscopy Bronchoscopy Bronchoscopy is a direct visual examination of the voice box (larynx) and airways through a viewing tube (a bronchoscope). A bronchoscope has a camera at the end that allows a doctor to look... read more (inserting a viewing tube into the bronchus), or both may be done to find the cause.
People who smoke can decrease their risk of atelectasis after surgery by stopping smoking Smoking Cessation While often very challenging, quitting smoking is one of the most important things smokers can do for their health. Quitting smoking brings immediate health benefits that increase over time... read more , ideally 6 to 8 weeks before surgery. After surgery, people are encouraged to breathe deeply, cough regularly, and move about as soon as possible. The use of devices to encourage voluntary deep breathing, called incentive spirometry Breathing exercises Respiratory therapists use several different techniques to help treat lung disease, including Postural drainage Suctioning Breathing exercises The choice of therapy is based on the underlying... read more , and certain exercises, including changing position to increase the drainage of lung mucus and other secretions, may help prevent atelectasis.
Atelectasis may be prevented by making sure deep breathing occurs. Whenever possible, conditions that cause shallow breathing for long periods should be treated.
Treatment of atelectasis may involve making sure deep breathing occurs, relieving airway blockages, or both.
Sometimes blockages can be relieved when a patient’s airway is suctioned by a health care practitioner. A blockage that cannot be removed by suctioning may require removal by bronchoscopy Bronchoscopy Bronchoscopy is a direct visual examination of the voice box (larynx) and airways through a viewing tube (a bronchoscope). A bronchoscope has a camera at the end that allows a doctor to look... read more . Sometimes other methods are necessary. For example, if a tumor is blocking an airway, the blockage can sometimes be relieved by surgery, radiation therapy, chemotherapy, or laser treatment. If mucus is plugging the airways, doctors sometimes give drugs to try to thin the mucus or open the airways.
Symptoms and complications of atelectasis may require treatment. People may require
Antibiotics, if bacterial infection is suspected
Rarely, insertion of a breathing tube (endotracheal intubation) and mechanical ventilation Mechanical Ventilation Mechanical ventilation is use of a machine to aid the movement of air into and out of the lungs. Some people with respiratory failure need a mechanical ventilator (a machine that helps air get... read more