Inheritance Pattern | Chance of Inheriting the Disorder | Chance of Being a Carrier* |
---|---|---|
Autosomal dominant | 50% for sons and daughters | 0% |
Autosomal recessive | 25% for sons and daughters if both parents are carriers (each parent has one abnormal gene)* 0% if only 1 parent is a carrier | 50% for sons and daughters, if both parents or only 1 parent is a carrier* |
X-linked dominant | 50% when the mother has the gene, usually only in daughters because the abnormal gene is often lethal in sons | 0% |
X-linked recessive | 50% for sons when the mother has the gene | 50% for daughters when the mother has the gene 100% for daughters when the father has the gene |
* Carriers have only one abnormal gene and usually have no symptoms of the disorder that the gene causes. | ||
See also Carrier Screening Genetic Carrier Screening Genetic disorders are caused by abnormalities in one or more genes or chromosomes. Some genetic disorders are hereditary and others are spontaneous. Hereditary genetic disorders are passed down... read more and Inheritance of Single-Gene Disorders Inheritance of Single-Gene Disorders Genes are segments of deoxyribonucleic acid (DNA) that contain the code for a specific protein that functions in one or more types of cells in the body or code for functional RNA molecules.... read more . |