MSD Manual

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Effects of Amyloid Buildup

Effects of Amyloid Buildup

Organ or System Affected

Possible Consequences

Blood vessels

Easy bruising

Brain

Digestive system

Constipation or diarrhea

Enlarged tongue (macroglossia)

Weight loss

Poor nutrient absorption

Heart

Kidneys

Fluid accumulation in tissues, causing swelling (edema)

Liver

Enlarged liver

Lungs and airway

Difficulty breathing

Wheezing

Lymph nodes

Enlarged lymph nodes

Musculoskeletal system

Nervous system

Numbness

Tingling

Light-headedness

Skin

Bruises

Nodules

Thyroid gland

Enlarged thyroid gland