MSD Manual

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Conditions That Occur With Certain Multiple Endocrine Neoplasia Syndromes

Conditions That Occur With Certain Multiple Endocrine Neoplasia Syndromes

Condition

MEN 1

MEN 2A

MEN 2B

Hyperparathyroidism (high levels of parathyroid hormone)

95% or more

10–20%

30–80%

Pituitary gland tumors

15–42%

Thyroid gland tumors (specifically medullary carcinoma)

More than 95%

More than 95%

Pheochromocytoma (tumor of the adrenal glands)

40–50%

50%

Neuromas (growths around nerves) on mucous membranes

Almost 100%

Physical characteristics similar to those in people with Marfan syndrome

Almost 100%

MEN = multiple endocrine neoplasia.